Share:
Share this content in WeChat
X
Clinical Article
MRI, SPECT and 2D echocardiography in assessing cardiac function of patients with idiopathic dilated cardiomyopathy
YANG Xiao-tang  LI Si-jin  PENG Kun  LIU Qi-wang  FENG Yan-lin  LI Jian-ying 

DOI:10.3969/j.issn.1674-8034.2010.03.007.


[Abstract] Objective: To compare two-dimensional echocardiography (2DE), SPECT and MRI for evaluation of cardiac function in patients with idiopathic dilated cardiomyopathy (IDCM).Materials and Methods: Cardiac MRI, gated SPECT and 2DE were performed in 42 IDCM patients. NYHA functional classification: 11 cases of class I-II, 16 cases of class III, 15 cases of class IV. Left ventricular (LV) function and volumes were measured using Simspon for 2DE, QGS software for gated SPECT, and ARGUS auto-quantitative program for MRI.Results: The correlation between MRI and gated SPECT (r≥0.9, P≤0.001), 2DE (r=0.699-0.878, P≤0.001) was good for the assessment of LVEF, EDV and ESV. There was significant difference between MRI and SPECT, 2DE in the estimation of LV volume, but EDV and ESV were underestimated by SPECT and 2DE. Comparing with MRI, the EF was underestimated by 2DE, but not by SPECT. MRI with NYHA classification: ESV, SV, EF, PER, PFR, EDD and ESD of class III/IV compared with class I-II had significance; 2DE with NYHA classification: ESV and EF of class III/IV compared with class I-II had significance, EDD and ESD IV compared with class I-II had significance; SPECT with NYHA classification: ESV and EF of class III/IV compared with class I-II had significance.Conclusion: Gated SPECT and 2DE correlate well for the assessment of LV function and volumes. However, both 2DE and SPECT underestimated LV volumes. Comparing with 2DE or SPECT, MRI can provide more information about LV function and volumes. These three methods have good correlation with the NYHA functional classification.
[Keywords] Cardiomyopathy, dilated;Tomography, emission-computed, single-photon;Magnetic resonance imaging;Echocardiography;Ventricular function, left

YANG Xiao-tang* Department of Radiology, the First Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, China

LI Si-jin Department of Nuclear Medicine, the First Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, China

PENG Kun Department of Radiology, Taigang General Hospital Affiliated to Shanxi Medical University, Taiyuan 030003, China

LIU Qi-wang Department of Radiology, the First Affiliated Hospital of Shanxi Medical University, Taiyuan 030001, China

FENG Yan-lin Department of Radiology, Taigang General Hospital Affiliated to Shanxi Medical University, Taiyuan 030003, China

LI Jian-ying Department of Radiology, Taigang General Hospital Affiliated to Shanxi Medical University, Taiyuan 030003, China

*Correspondence to: Yang XT, E-mail: yxtbean@126.com

Conflicts of interest   None.

Received  2010-01-13
Accepted  2010-03-06
DOI: 10.3969/j.issn.1674-8034.2010.03.007
DOI:10.3969/j.issn.1674-8034.2010.03.007.

[1]
O'Rourke RA, Hanrath P, Henry WN, et al. Report of the Joint International Society and Federation of Cardiology/World Health Organization Task Force on Recommendations for Standardization of Measurements from M-mode Echocardiograms. Circulation, 1984, 69(4): 854A-857A.
[2]
Li KC, Zhao XG. Assessment of Left ventricular Function in Patients with Dilat ed Cardiomyopathy Using Cine Magnetic Resonance Imaging. Chin J Med Imaging Technol, 2002,18(5):443-445.
[3]
Germans T, Rossum AC. The use of cardiac magnetic resonance imaging to determine the aetiology of left ventricular disease and cardiomyopathy. Heart,2008,94(4):510-518.
[4]
Editorial Committee of Chinese Journal of Cardiology. Summary of the symposium on Chinese myocarditis and cardiomyopathy. Chin J Cardiol, 1999,27(6):408-412.
[5]
Juha R, Margareta Antila, Jyrki M, et al. Early Familial Dilated Cardiomyopathy Identification with Determination of Disease State Parameter from Cine MR Image Data. Radiology, 2008, 249(1): 88-96.
[6]
Berk F, Isgoren S, Demir H, et al. Assessment of left ventricular function and volumes for patients with dilated cardiomyopathy using gated myocardial perfusion SPECT and comparison with echocardiography. Nucl Med Commun, 2005, 26(8):701-710.
[7]
Matsuo S, Nakae I, Tsutamoto T, et al. A novel clinical indicator using Tc-99m sestamibi for evaluating cardiac mitochondrial function in patients with cardiomyopathies. J Nucl Cardiol, 2007,14(2):215-220.
[8]
Ji FS, Li W, Zhang RN, et al. Value of 99mTc-MIBI scintigraphy for distinction of ischemic from dilated cardiomyopathy. Chin J Cardiol, 2003, 31(12): 932-934.
[9]
Chan J, Jenkins C, Khafagi F, et al. What is the optimal clinical technique for measurement of left ventricular volume after myocardial infarction? A comparative study of 3-dimensional echocardiography, single photon emission computed tomography, and cardiac magnetic resonance imaging. J Am Soc Echocardiogr, 2006, 19(2):192-201.
[10]
Knaapen P, Gotte MJ, Paulus WJ, et al. Does myocardial fibrosis hinder contractile function and perfusion in idiopathic dilated cardiomyopathy? PET and MR imaging study. Radiology, 2006, 240(2): 380-388.
[11]
Mor-Avi V, Sugeng L, Weinert L,et,al. Fast measurement of left ventricular mass with real-time three-dimensional echocardiography: comparison with magnetic resonance imaging. Circulation, 2004, 110(13):1814-1818.
[12]
Voormolen MM, Danilouchkine MG. Aspects of left ventricular volume comparison between 3D echocardiography and MRI. J Am Soc Echocardiogr, 2007, 20(12):1421-1422.

PREV Diffusion tensor MR imaging of cervical spinal cord: cervical spondylosis-related changes
NEXT Preoperative evaluation of hepatic hilar cholangiocarcinoma with enhanced MRI and MR cholangiopancreatography
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn