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• Clinical Article •
Diffusion-weighted MR imaging in assessment of primary adrenal tumors at 3.0 T
YU Xiao-duo  LIN Meng  HU Man-cang  OUYANG Han  ZHOU Chun-wu 

DOI:10.3969/j.issn.1674-8034.2010.05.011.


[Abstract] Objective: To evaluate the value of diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) at 3.0 T MR in primary adrenal tumors.Materials and Methods: DWI images of 48 patients with primary adrenal tumors proved by surgical pathology were retrospectively reviewed. ADC values of tumors were statistically analyzed.Results: The mean ADC value of neoplasms were listed below: ganglioneuromas (n=5), 1.948±0.357×10-3 mm2/s; benign pheochromocytomas (n=7, including 1 case with bilateral tumor), 1.666±0.547×10-3 mm2/s; cortical adenomas (n=21), 1.434±0.430×10-3 mm2/s; primary adrenal malignant tumors(n=8, including 7 adrenal cortical carcinomas and 1 malignant pheochromocytoma), 0.951±0.144×10-3 mm2/s; myelolipomas (n=7), 0.764±0.209×10-3 mm2/s. Except myelolipomas, given ADC value of 1.08×10-3 mm2/s as a threshold for diagnosing primary adrenal malignant tumor, the sensitivity, specificity and accuracy were 87.50%, 85.29% and 85.71%, respectively. There were significant differences between primary adrenal tumors and ganglioneuromas, benign pheochromocytomas and cortical adenomas (P=0.003, 0.006 and 0.001, respectively). However, no statistic difference was found between primary adrenal malignant tumors and myelolipomas.Conclusion: 3.0 T MR DWI could be used in diagnosis of primary adrenal tumors, and ADC value might be helpful in differentiating the adrenal pathology.
[Keywords] Magnetic resonance imaging；Diffusion weighted imaging；Adrenal gland neoplasms

YU Xiao-duo Department of Diagnostic Imaging, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China

LIN Meng Department of Diagnostic Imaging, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China

HU Man-cang Department of Diagnostic Imaging, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China

OUYANG Han* Department of Diagnostic Imaging, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China

ZHOU Chun-wu Department of Diagnostic Imaging, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China

*Correspondence to: Ouyang H, E-mail: hbybj@sohu.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  Supported by Beijing Hope Run Special Fund 基金编号: LC2008A02
Received  2010-03-10
Accepted  2010-06-16
DOI: 10.3969/j.issn.1674-8034.2010.05.011
DOI:10.3969/j.issn.1674-8034.2010.05.011.

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