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The definitions and diagnostic criteria of vulnerable plaque
ZHAO Shi-hua 

DOI:10.3969/j.issn.1674-8034.2010.06.003.


[Abstract] Vulnerable plaque was also called high-rish plaque, dangerous plaque, unstable plaque, soft plaque, non-calcified plaque or AHA type IV plaque, etc. In 2003, Naghavi et al established the diagnostic criteria for detection of vulnerable plaque based on the autopsy results, the major criteria included the following features: (1) Active inflammation, (2) A thin cap with a large lipid core, (3) Endothelial denudation with superficial platelet aggregation, (4) Fissured/Injured plaque, (5) Severe stenosis; the minor criteria included (1) Superficial calcified nodules, (2) Yellow color (on angioscopy), (3) Intraplaque hemorrhage, (4) Endothelial dysfunction, (5) Expansive (Positive) remodeling. The article stressed upon reviewing the diagnostic criteria.
[Keywords] Vulnerable plaque；Definition；Diagnostic criteria

ZHAO Shi-hua Department of Radiology, Cardiovascular Institute & Fu Wai Hospital, CAMS & PUMC, Beijing 100037, China

*Correspondence to: Zhao SH, E-mail: cjr.zhaoshihua@vip.163.com

Conflicts of interest   None.

Received  2010-09-10
Accepted  2010-10-14
DOI: 10.3969/j.issn.1674-8034.2010.06.003
DOI:10.3969/j.issn.1674-8034.2010.06.003.

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