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• Clinical Article •
Three-dimensional MR imaging in detection of congenital malformations of fetal colon
SUN Zi-yan  XIA Li-ming  WANG Cheng-yuan  YANG Xiao-hong 

DOI:10.3969/j.issn.1674-8034.2010.06.010.


[Abstract] Objective: To investigate the clinical value of three-dimensional MR imaging (3D-MRI) in displaying the normal and abnormal fetal colon.Materials and Methods: Thirty-eight pregnant women (gestational age ranged from 19-37 weeks, mean of 28.5 weeks) diagnosed or suspected of fetal malformations underwent conventional prenatal US and MRI. Sagittal and coronal SSFSE T2WI examinations by a 1.5 T GE superconducting MR scanner within 1-2 days after US examinations were performed. 3D MR colonography (3D-MRC) were performed with 3D fast spoiled gradient echo (3D-FSPGR). Volume rendering (VR), maximum intensity projection (MIP), multi-planar reconstruction (MPR), and MR virtual colonoscopy (MRVC) were employed in image post-processing on a dedicated workstation, the volume of normal colon between 19 and 37 weeks was measured. The MRI and US appearances of fetal malformations were compared to each other, autopsy, and follow-up results.Results: The acquisition time and reconstruction time of 3D-MRC during a single breath-hold is 10-14 seconds and 5-10 minutes, respectively. The success rate was up to 89.47%(34/38). Fetal colon showed high signal intensity on 3D-MRC, similar to the findings obtained by Barium enema in neonates. MPR, VR, and MRVC could clearly display normal colonic topography, haustra of colon, and flexures. The region of interest could be viewed from various directions by using MPR. Dilatation and stenosis of intestinal lumen were displayed by using MRVC. The range of colon volumes between 19 and 37 weeks was 5.1 to 69.2 ml. The transverse diameter of colon during fetal period was lesser than 1.8 cm. Colonic atresia (3 cases), congenital left diaphragmatic hernia (3 cases), and congenital magacolon (2 cases) as well as cloacal exstrophy (1 case) were detected and diagnosed by 3D-MRC.Conclusion: 3D-MRC is feasible in clinical practice, which is helpful for antepartum console and planning of fetal surgery.
[Keywords] Fetus；Congenital colon abnormality；Meconium；MR colonography；Magnetic resonance imaging

SUN Zi-yan Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

XIA Li-ming* Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

WANG Cheng-yuan Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

YANG Xiao-hong Hubei Maternal and Child Health Care Hospital, Wuhan, Hubei 430070, China

*Correspondence to: Xia LM, E-mail: xialiming88@yahoo.com.cn

Conflicts of interest   None.

Received  2010-03-05
Accepted  2010-08-12
DOI: 10.3969/j.issn.1674-8034.2010.06.010
DOI:10.3969/j.issn.1674-8034.2010.06.010.

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