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• Clinical Article •
MR imaging for graft non-neoplastic lesions after liver transplantation
MENG Xiao-chun  LIU Wei-min  TANG Wen-jie  GUO Yue-fei  FANG Yuan  JIANG Ting  KANG Zhuang  SHAN Hong 

DOI:10.3969/j.issn.1674-8034.2010.06.011.


[Abstract] Objective: To discuss the role of MR examination for graft non-neoplastic lesions after liver transplantation and the clinical value of MR results.Materials and Methods: From Jan 2005 to Dec 2009, 23 receptors received MR examination during the follow-up period and were detected graft non-neoplastic lesions. Post-operative histopathology or biopsy confirmed moderate/severe acute rejection in 9 cases, inflammatory lesions in 4 cases (3 with liver abscess, 1 with eosinophilic granuloma), liver ischemia or infarction in 3 cases; liver congestion in 2 cases; fatty liver in 2 cases. Long-term follow-up confirmed hepatic arteriovenous shunt in 6 cases. Among them, 22 received orthotopic liver transplantation and the other one received right lobe living donor liver transplantation. We discussed the MR performances of above non-neoplastic lesions and its role for the etiological diagnosis.Results: Based on MR examination, all the inflammatory lesions, liver ischemia, infarction, congestion and fatty liver were correctly diagnosed without missed diagnosis and misdiagnosis of cases. But in 1 case, according to MR performances, liver lesions only were judged as inflammatory, eosinophilic granuloma was not diagnosed. Intrahepatic peripheral arteriovenous shunt was correctly diagnosed in 5/6 cases based on the first MR examination, and 1 case was confirmed in the follow-up period. In the patients with acute rejection, MR signal was normal in 7/9 cases and abnormal in 2/9 cases only with homogeneous or patchy slightly higher signal in T2WI. All cases were not diagnosed in MR examinations. Based on LAVA data, MR angiography (MRA) presented all the vascular complications confirmed by DSA for the patients with graft ischemia, infarction or congestion, including 3 hepatic artery stenosis, 1 portal venous stenosis, 1 middle hepatic vein stenosis and 1 middle hepatic vein occlusion. In the 3 cases with liver abscess, 2 were detected ischemic biliary stricture in MR Cholangiopancreatography and hepatic artery stenosis in MRA.Conclusion: MR examination played an important role in deciding the location, property and etiology for graft non-neoplastic lesions after liver transplantation. However, it could not help for the non-invasive diagnosis of acute rejection.
[Keywords] Liver transplantation；Complications；Graft, non-neoplastic lesions；Magnetic resonance imaging

MENG Xiao-chun Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

LIU Wei-min Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

TANG Wen-jie Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

GUO Yue-fei Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

FANG Yuan Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

JIANG Ting Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

KANG Zhuang Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

SHAN Hong* Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China

*Correspondence to: Shan H, E-mail: shanhong5@gmail.com

Conflicts of interest   None.

Received  2010-06-08
Accepted  2010-08-20
DOI: 10.3969/j.issn.1674-8034.2010.06.011
DOI:10.3969/j.issn.1674-8034.2010.06.011.

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