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• Clinical Article •
High resolution MR angiography of digital arteries in systemic sclerosis patients on 3.0 T: preliminary study
ZHANG Wei  XU Jian-rong  LU Qing  YE Shuang  LIU Xiao-sheng 

DOI:10.3969/j.issn.1674-8034.2011.02.002.


[Abstract] Objective: We sought to evaluate the use of high-resolution three-dimensional time-of-flight (3D-TOF) MRA at 3.0 T in the visualization of digital arteries in systemic sclerosis (SSc) patients.Materials and Methods: Thirty patients with SSc(mean±SD age 35.4 ± 8.9 years, median number of years since onset of Raynaud's phenomenon 3.2 ± 2.7 years) and 7 healthy controls (mean ± SD age 30.7 ± 3.5 years) were examed on a 3.0 T MR system. A modified high-spatial-resolution(voxel size=0.35 × 0.35 × 0.5 mm3) 3D-TOF MRA (TR/TE=19/4.4 ms, FA = 15°, slice thickness = 1 mm) were performed during a total scan time of 8 min 22 s. The source images and MIP reconstruction were studied, the digital arteries count and lumen area of the selective section of the vessel were measured independently by two experienced radiologists and compared with that of the control ones, and a four-level grading system was made according to the severity. Statistical analysis was performed with t test and P < 0.05 was used as the criterion.Reults: We detected the 8 digital arteries in the four fingers(without the thumb) of each case and got a 47.58% presentation in general in SSc group, and artery No.5 had the highest presentation rate (70.97%). Statistics showed the digital artery No.1 (P= 0.058) and No.3 (P= 0.093) had no difference in the lumen area (P>0.05).Conclusion: MR angiography of the digital arteries in the described technique is a promising method for us to judge the severity of finger vessels involved in SSc patients.
[Keywords] MR Imaging；Micro-MR angiography；MIP；Three-dimensional time-of-flight；Proper digital artery；Systemic sclerosis；Raynaud's phenomenon；Vascular abnormalities

ZHANG Wei Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China

XU Jian-rong* Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China

LU Qing Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China

YE Shuang Shanghai Clinical Centre of Rheumatic Diseases and Institute of Rheumatology, Department of Rheumatism, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China

LIU Xiao-sheng Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China

*Correspondence to: Xu JR, E-mail: xjrong@gmail.com

Conflicts of interest   None.

Received  2010-12-20
Accepted  2011-02-06
DOI: 10.3969/j.issn.1674-8034.2011.02.002
DOI:10.3969/j.issn.1674-8034.2011.02.002.

[1]
Herrick AL. Pathogenesis of Raynaud's phenomenon. Rheumatology, Oxford, 2005, 44(5):587-596.
[2]
Kahaleh MB. Vascular involvement in systemic sclerosis. Clin Exp Rheumatol, 2004, 22(Suppl 33):S19-S23.
[3]
Herrick AL. Vascular function in systemic sclerosis. Curr Opin Rheumatol, 2000, 12(6):527-533.
[4]
Tamborrini G, Distler M, Distler O. Systemic sclerosis. Med Monatsschr Pharm, 2008, 31(5):162-170.
[5]
Serena G, Roberto G, Marco MC. Vascular complications of scleroderma. Autoimmunty Reviews, 2007, 6(8):520-523.
[6]
Gayraud M. Raynaud's phenomenon. Joint Bone Spine, 2007, 74(1):e1-e8.
[7]
Ostojic P, Damjanov N, Pavlov-Dolijanovic S, et al. Peripheral vasculopathy in patients with systemic sclerosis: Difference in limited and diffuse subset of disease. Clin Hemorheol Microcirc, 2004, 31(4):281-285.
[8]
Alfonse T. Masi. Subcommittee for Scleroderma Criteria of the American Rheumatism Association iagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum, 1980, 23(5):581-590.
[9]
David A, Connell F, George K, et al. Contrast-enhanced MR Angiography of the Hand. Radiographics, 2002, 22(5):583-599.
[10]
Hinchcliff M, Varga J. Systematic sclerosis/scleroderma:a treatable multisystem disease. Am Fam Physician, 2008, 78(8):961-968.
[11]
Stucker M, Quinna S, Memmel U, et al. Macroangiopathy of the upper extremities in progressive systemic sclerosis. Eur J Med Res, 2000, 5(7):295-302.
[12]
Hasegawa M, Nagai Y, Tamura A, et al. Arteriographic evaluation of vascular changes of the extremities in patients with systemic sclerosis. Br J Dermatol, 2006, 155(6):1159-1164.
[13]
Merkel PA, Herlyn K, Martin RW, et al. Measuring disease activity and functional status in patients with scleroderma and Raynaud's phenomenon. Arthritis Rheum, 2002, 46(9):2410-2420.
[14]
Chung L, Fiorentino D. Digital ulcers in patients with systemic sclerosis. Autoimmun, 2006, 5(2):125-128.
[15]
Wang J, Yarnykh VL, Molitor JA, et al. Micro magnetic resonance angiography of the finger in systemic sclerosis. Rheumatology, 2008, 47(8):1239-1243.
[16]
Kambiz NJ, Pablo V, Whitney B, et al. Supraaortic Arteries: Contrastenhanced MR Angiography at 3.0T-Highly Accelerated Parallel Acquisition for Improved Spatial Resolution over an Extended Field of View1. Radiology, 2007, 242(2):600-609.
[17]
Connell DA, Koulouris G, Thorn DA, et al. Contrast-enhanced MR angiography of the hand. Radiographics, 2002, 22(3):583-599.
[18]
Brauck K, Maderwald S, Vogt FM, et al. Time-resolved contrast-enhanced magnetic resonance angiography of the hand with parallel imaging and view sharing: initial experience. Euro Radiology, 2007, 17(1):183-192.
[19]
Rofsky NM. MR angiography of the hand and wrist. Magn Reson Imaging Clin N Am, 1995, 3(2):345-359.
[20]
Allanore Y, Seror R, Chevrot A,, et al. Hand Vascular Involvement Assessed by Magnetic Resonance Angiography in Systemic Sclerosis. Arthritis Rheum, 2007, 56(8):2747-2754.
[21]
Keberle M, Tony HP, Jahns R, et al. Assessment of microvascular changes in Raynaud's phenomenon and connective tissue disease using colour Doppler ultrasound. Rheumatology (Oxford), 2000, 39(11):1206-1213.
[22]
Schmidt WA, Wernicke D, Kiefer E, et al. Colour duplex sonography of finger arteries in vasculitis and in systemic sclerosis. Ann Rheum Dis, 2006, 65(2):265-267.

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