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Clinical Article
Value of MR imaging in early rheumatoid arthritis
DENG Xia  XU Jian-rong  LU Qing  LI Lei 

DOI:10.3969/j.issn.1674-8034.2011.02.004.


[Abstract] Objective: To discuss the role of MR imaging in early rheumatoid arthritis (ERA).Materials and Methods: The study group consisted of 35 patients diagnosed ERA. All the conventional X-ray and MRI images of wrists and fingers were reviewed. All the MRI examinations were performed on a Philips Achieva 3.0 T sacanner.Results: Abnormalities in 35 ERA patients included synovitis, tenosynovitis, joint effusion, bone marrow edema and bone erosions. MRI revealed synovitis in 33 of 35 (94.3%), showing thickened synovium and obvious enhancement after the administration of gadolinium. Tenosynovitis was shown as thickened synovium around the tendon or effusion under the synovial sheath. The extensor carpi ulnaris was the most involved in 20 of 28 (71.4%). Twenty-seven bone erosions were revealed in 25 patients on MRI. MRI was statistically more sensitive than conventional radiography for detecting bone erosions in RA, P<0.01. Bone marrow edema in 15 patients appeared as a lesion with ill-defined margins and high signal, located surrounding the bone erosions.Conclusion Bone erosions may be found in the early process of RA. Abnormalities of synovium, synovial sheath and bone can be well described on MRI. MRI is a useful modality for evaluation of patients with early rheumatoid arthritis.
[Keywords] Magnetic resonance imaging;Rheumatoid arthritis;Early diagnosis;Bone erosion;Synovitis;Tenosynovitis;Hydrarthrosis;Bone marrow edema;Synovial hyperplasia

DENG Xia Department of Radiology, Renji Hospital, Medical College of Shanghai Jiao Tong University, Shanghai 200127, China

XU Jian-rong* Department of Radiology, Renji Hospital, Medical College of Shanghai Jiao Tong University, Shanghai 200127, China

LU Qing Department of Radiology, Renji Hospital, Medical College of Shanghai Jiao Tong University, Shanghai 200127, China

LI Lei Department of Radiology, Renji Hospital, Medical College of Shanghai Jiao Tong University, Shanghai 200127, China

*Correspondence to: Xu JR, E-mail: xujianr@hotmail.com

Conflicts of interest   None.

Received  2010-12-20
Accepted  2011-02-06
DOI: 10.3969/j.issn.1674-8034.2011.02.004
DOI:10.3969/j.issn.1674-8034.2011.02.004.

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