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• Clinical Article •
Application of magnetic resonance diffusion tensor imaging and fiber tractography to evaluate the value of diagnostic classification of cerebral gliomas
HU Hong-bo  LIU Peng-fei 

DOI:10.3969/j.issn.1674-8034.2011.02.009.


[Abstract] Objective: To evaluate the brain gliomas by the combination of diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT), and to discuss its value in cerebral gliomas diagnostic classification.Materials and Methods: Conventional MRI and DTI were performed in 25 patients with histological confirmed as gliomas which conclude 9 low-grade gliomas (WHO grade I-II) , 16 high-grade gliomas (WHO grade Ⅲ-Ⅳ). The values of FA and MD were calculated in the patients’ tumor center. The clinical benefit of DTT in display the brain white matter fiber was evaluated.Results: There was significant difference of FA values in the solid part of tumors between low-grad gliomas and high-grade gliomas (P < 0.05). The MD values in tumors center were different, but no statistical significance (P > 0.05). On the DTT map, 7 of 9 low grade gliomas showed fiber bundle deviation, 2 of 9 low grade gliomas show partly interruption; 15 high grade gliomas patients’ fiber bundle were deviated, 14 of 15 high grade gliomas patients’ fiber were obviously destructed. But mainly appear as fiber deviation in 1 gliomas patient.Conclusion: Combination of DTI and DTT could be helpful in judging the degree of the tumor and accurately show the relationship of tumor and surrounding white matter fiber clearly, and provide more information of differential diagnosis. It is great value in surgical plan for patients with cerebral gliomas.
[Keywords] Diffusion tensor imaging；Diffusion tensor tractography；Gliomas

HU Hong-bo Department of Radiology, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

LIU Peng-fei* Department of Radiology, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

*Correspondence to: Liu PF, E-mail: liupengfei@54dr.com

Conflicts of interest   None.

Received  2010-04-01
Accepted  2010-12-28
DOI: 10.3969/j.issn.1674-8034.2011.02.009
DOI:10.3969/j.issn.1674-8034.2011.02.009.

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