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• Clinical Article •
Clinical significance of time-signal intensity curve type I on dynamic contrast-enhanced MRI of the breasts
GU Shuang  SU Tian-hao  JIN Er-hu  LIANG Yu-ting  MA Da-qing 

DOI:10.3969/j.issn.1674-8034.2011.03.006.


[Abstract] Objective: To explore the value of time-signal intensity curve (TIC) type I in identifying enhanced lesions of the breasts on dynamic contrast-enhanced MRI (DCE-MRI).Materials and methods: Fifty-three patients with breast lesions performed MRI examinations at 3.0 T scanner. Numbers and features of the lesions were analyzed on axial FSE T1WI, axial and sagittal STIR T2WI, and 3-dimentional DCE-MRI after intravenous gadolinium administration. TIC types of the enhanced lesions were classified according to their shapes as type I, which was steady enhancement; type II, plateau of signal intensity; or type III, washout of signal intensity.Results: Among fifty-three female patients, abnormally enhanced lesions with TIC type I on DCE-MRI included benign lesions in 36 (breast adenosis 17, breast cystic hyperplasia 4, breast fibroadenoma 13, intraductal papilloma 2), untreated malignant lesions in 8 (ductal carcinoma in situ 3, mucinous carcinoma 4, invasive ductal carcinoma 1) and residual lesions of breast carcinoma following neoadjuvant chemotherapy in 9.Conclusion: TIC type I may be found in both benign and malignant lesions of the breasts, it is necessary to combine with morphological characteristics and clinical history for a correct judgment.
[Keywords] Breast diseases；Breast carcinomas；Magnetic resonance imaging

GU Shuang Department of Radiology, Fuxing Hospital, Capital Medical University, Beijing 100038, China

SU Tian-hao Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

JIN Er-hu* Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

LIANG Yu-ting Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

MA Da-qing Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

*Correspondence to: Jin EH, E-mail: erhujin@263.net

Conflicts of interest   None.

Received  2010-10-20
Accepted  2011-03-11
DOI: 10.3969/j.issn.1674-8034.2011.03.006
DOI:10.3969/j.issn.1674-8034.2011.03.006.

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