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• Clinical Article •
Comparison of different MRI sequences in cervical spinal cord injury
WANG Mei-yun  HAN Yan-hong  DAI Jian-ping  DAI Yong-ming  SHI Da-peng 

DOI:10.3969/j.issn.1674-8034.2011.03.007.


[Abstract] Objective: To compare conventional MRI, gradient-echo (GRE) T2*-weighted imaging (WI) and susceptibility weighted imaging (SWI) in acute cervical spinal cord injury (SCI).Materials and Methods: Conventional T1WI, T2WI, GRE T2*WI and high-resolution SWI were performed on sixteen patients with a history of acute cervical spine traumaby using a 3 Tesla MRI system (TrioTim, Siemens Medical Solution). The MRI findings on each sequence was observed and classified into 4 types: normal cord, spinal cord edema, spinal cord contusion and spinal cord hemorrhage. The signal intensity in the hemorrhage and normal spinal cord were measured on the same slice of T2*WI and SWI, respectively, and the ratio of the hemorrhage to normal spinal cord were calculated and compared by using Wilcoxon signed ranks test. All patients were also evaluated with clinical follow-up. Twenty volunteers were scanned as a control group.Results: In 16 patients with acute cervical spine trauma, conventional T1WI and T2WI showed normal in 2 cases and SCI in 14 patients, in which 6 patients had spinal cord edema, 4 had contusion and 4 had hemorrhage. However, both SWI and T2*WI demonstrated normal in 10 cases and detected hemorrhage in 6 patients, in which only 4 patients were detected hemorrhage by conventional MRIs, the other 2 patients were showed spinal contusion on conventional MRIs. The mean signal ratio of hemorrhage to normal tissue was 0.58 on T2*WI and 0.47 on SWI, and a significant difference was revealed between them (Z=2.33, P=0.02).Conclusion: Conventional MRI including T1WI and T2WI is valuable in demonstrating spinal edema and contusion, but not very sensitive to spinal hemorrhage. SWI is more sensitive than T2*WI in detecting hemorrhage in acute cervical SCI and could be included in the routine evaluation of cervical SCI patients.
[Keywords] Susceptibility weighted imaging；Magnetic resonance imaging；Spinal cord injuries；Trauma

WANG Mei-yun Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

HAN Yan-hong Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

DAI Jian-ping Neuroimaging center, the Affiliated Beijing Tiantan Hospital of Capital Medical University, Beijing 100050, China

DAI Yong-ming MRI, Siemens Healthcare, Shanghai, 201318, China

SHI Da-peng* Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

*Correspondence to: Shi DP, E-mail: cjr.shidapeng@vip.163.com

Conflicts of interest   None.

致谢： 感谢李永丽、连建敏、窦社伟、闫峰山、林青、王莹、王曼等在收集数据方面的帮助。
Received  2011-02-20
Accepted  2011-04-06
DOI: 10.3969/j.issn.1674-8034.2011.03.007
DOI:10.3969/j.issn.1674-8034.2011.03.007.

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