Share：
Share this content in WeChat
X
[Chinese][PDF]788119
• Clinical Article •
Comparison of different MRI sequences in cervical spinal cord injury
WANG Mei-yun  HAN Yan-hong  DAI Jian-ping  DAI Yong-ming  SHI Da-peng 

DOI:10.3969/j.issn.1674-8034.2011.03.007.


[Abstract] Objective: To compare conventional MRI, gradient-echo (GRE) T2*-weighted imaging (WI) and susceptibility weighted imaging (SWI) in acute cervical spinal cord injury (SCI).Materials and Methods: Conventional T1WI, T2WI, GRE T2*WI and high-resolution SWI were performed on sixteen patients with a history of acute cervical spine traumaby using a 3 Tesla MRI system (TrioTim, Siemens Medical Solution). The MRI findings on each sequence was observed and classified into 4 types: normal cord, spinal cord edema, spinal cord contusion and spinal cord hemorrhage. The signal intensity in the hemorrhage and normal spinal cord were measured on the same slice of T2*WI and SWI, respectively, and the ratio of the hemorrhage to normal spinal cord were calculated and compared by using Wilcoxon signed ranks test. All patients were also evaluated with clinical follow-up. Twenty volunteers were scanned as a control group.Results: In 16 patients with acute cervical spine trauma, conventional T1WI and T2WI showed normal in 2 cases and SCI in 14 patients, in which 6 patients had spinal cord edema, 4 had contusion and 4 had hemorrhage. However, both SWI and T2*WI demonstrated normal in 10 cases and detected hemorrhage in 6 patients, in which only 4 patients were detected hemorrhage by conventional MRIs, the other 2 patients were showed spinal contusion on conventional MRIs. The mean signal ratio of hemorrhage to normal tissue was 0.58 on T2*WI and 0.47 on SWI, and a significant difference was revealed between them (Z=2.33, P=0.02).Conclusion: Conventional MRI including T1WI and T2WI is valuable in demonstrating spinal edema and contusion, but not very sensitive to spinal hemorrhage. SWI is more sensitive than T2*WI in detecting hemorrhage in acute cervical SCI and could be included in the routine evaluation of cervical SCI patients.
[Keywords] Susceptibility weighted imaging；Magnetic resonance imaging；Spinal cord injuries；Trauma

WANG Mei-yun Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

HAN Yan-hong Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

DAI Jian-ping Neuroimaging center, the Affiliated Beijing Tiantan Hospital of Capital Medical University, Beijing 100050, China

DAI Yong-ming MRI, Siemens Healthcare, Shanghai, 201318, China

SHI Da-peng* Department of Radiology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450003, China

*Correspondence to: Shi DP, E-mail: cjr.shidapeng@vip.163.com

Conflicts of interest   None.

致谢： 感谢李永丽、连建敏、窦社伟、闫峰山、林青、王莹、王曼等在收集数据方面的帮助。
Received  2011-02-20
Accepted  2011-04-06
DOI: 10.3969/j.issn.1674-8034.2011.03.007
DOI:10.3969/j.issn.1674-8034.2011.03.007.

[1]
Kulkarni MV, McArdle CB, Kopanicky D, et al. Acute spinal cord injury: MR imaging at 1.5 T. Radiology, 1987, 164(3):837-843.
[2]
Katzberg RW, Benedetti PF, Drake CM, et al.Acute cervical spine injuries: prospective MR imaging assessment at a level 1 trauma center. Radiology, 1999, 213(1):203-212.
[3]
Shin JC, Kim DY, Park CI, et al. Neurologic recovery according to early magnetic resonance imaging findings in traumatic cervical spinal cord injuries. Yonsei Med J, 2005, 46(3):379-387.
[4]
Miyanji F, Furlan JC, Aarabi B, et al. Acute cervical traumatic spinal cord injury: MR imaging findings correlated with neurologic outcome-prospective study with 100 consecutive patients. Radiology, 2007, 243(3):820-827.
[5]
Mahmood NS, Kadavigere R, Avinash KR, et al.Magnetic resonance imaging in acute cervical spinal cord injury: a correlative study on spinal cord changes and 1 month motor recovery. Spinal Cord, 2008, 46(12):791-797.
[6]
Haacke EM, Mittal S, Wu Z, et al. Susceptibility-weighted imaging: technical aspects and clinical applications, part 1. AJNR Am J Neuroradiol, 2009, 30(1):19-30.
[7]
王丽娟，刘玉波，王光彬．磁敏感加权成像原理概述．磁共振成像, 2010, 1(3):227-230.
[8]
李秋云，肖恩华．磁敏感加权成像临床应用研究进展．磁共振成像，2010, 1(3):231-235.
[9]
朱文珍，漆剑频，申皓，等. MR磁敏感成像技术在脑部血管性病变中的应用．中华放射学杂志，2007, 41(10):1040-1044.
[10]
申宝忠,王丹,孙夕林,等. MR磁敏感成像在脑内出血性疾病中的应用.中华放射学杂志,2009, 43(2):156-160.
[11]
Santhosh K, Kesavadas C, Thomas B, et al. Susceptibility weighted imaging: a new tool in magnetic resonance imaging of stroke. Clinical Radiology, 2009, 64(1):74-83.
[12]
Ayaz M, Boikov A, Haacke EM, et al. Imaging cerebral microbleeds using susceptibility weighted imaging: one step toward detecting vascular dementia. J Magn Reson Imaging, 2010, 31(1):142-148.
[13]
American Spinal Injury Association, International Medical Society of Paraplegia (ASIA/IMSOP). International standards for neurological and functional classification of spinal cord injury. Revised 1992, American Spinal Injury Association, Chicago III.
[14]
Ditunno JF Jr, Young W, Donovan WH, et al. The international standards booklet for neurological and functional classification of spinal cord injury. Paraplegia, 1994, 32(2):70-80.
[15]
Reichenbach JR, Venkatesan R, Schillinger DJ, et al. Small vessels in the human brain: MR venography with deoxyhemoglobin as an intrinsic contrast agent. Radiology, 1997, 204(1):272-277.
[16]
Ramón S, Domínguez R, Ramírez L, et al. Clinical and magnetic resonance imaging correlation in acute spinal cord injury. Spinal Cord, 1997, 35(10):664-673.
[17]
Frankel HL, Hancock DO, Hyslop G, et al. The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia. Paraplegia, 1969, 7(3):179-192.
[18]
Bondurant FJ, Cotler HB, Kulkarni MV, et al. Acute spinal cord injury: a study using physical examination and magnetic resonance imaging. Spine, 1990, 15(3):161-168.
[19]
Bracken MB, Shepard MJ, Collins WF, et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury: results of the Second National Acute Spinal Cord Injury Study. N Engl J Med, 1990, 322(20):1405-1411.
[20]
Bradley WG Jr. MR appearance of hemorrhage in the brain. Radiology, 1993, 189(1):15-26.
[21]
Melki PS, Mulkern RV, Panvch LP, et al. Comparing the FAISE method with conventional dual-echo sequences. J Magn Reson Imaging, 1991, 1(3):319-326.

PREV Clinical significance of time-signal intensity curve type I on dynamic contrast-enhanced MRI of the breasts
NEXT Differential diagnosis between cerebral lymphoma and gliomas multiblastoma by using of apparent diffusion coefficient
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn