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Clinical Article
Clinical value of whole-body magnetic resonance diffusion weighted imaging in the screening of malignant tumor
ZHANG Yan  WANG Xi-xing  HUANG Yong-bo  WANG Jun 

DOI:10.3969/j.issn.1674-8034.2011.03.009.


[Abstract] Objective: To evaluate the value of whole-body magnetic resonance diffusion weighted imaging (WB-DWI) in the screening of malignant tumor.Materials and Methods: Ten healthy volunteers and 36 patients of clinically suspected malignant tumors underwent WB-DWI and conventional MRI (scanning CT if it is chest disease) enhancing the scanning when necessary. The medical results of WB-DWI and MRI/CT were compared with the findings of pathological diagnosis and clinical comprehensive evaluations.Results: Twenty-nine of 36 patients were diagnosed as malignant tumors by final pathological endings, the others were benign lessions. Twenty-eight of 36 patients were diagnosed as malignant tumors by WB-DWI, 1 were misdiagnosed, 2 were missed. The primary lesions of 20 patients were diagnosed by WB-DWI. The sensitivity, specificity, youden’s index and agreement/consistency rate were 93.1%, 85.7%, 0.79 and 91.7%. Six of 7 patients, abnormality of benign lesions were found by WB-DWI.Conclusion: WB-DWI have certain value in the screening of malignant tumor.
[Keywords] Magnetic resonance imaging;Whole body diffusion weighted imaging;Malignant tumor;Screening

ZHANG Yan* Shan Xi TCM Hospital, Taiyuan 030012, China

WANG Xi-xing Shan Xi TCM Hospital, Taiyuan 030012, China

HUANG Yong-bo The Second Hospital of Shanxi Medical University, Taiyuan 030001, China

WANG Jun The Second Hospital of Shanxi Medical University, Taiyuan 030001, China

*Correspondence to: Zhang Y, E-mail: mouseyanzhang@163.com

Conflicts of interest   None.

Received  2010-08-10
Accepted  2011-01-20
DOI: 10.3969/j.issn.1674-8034.2011.03.009
DOI:10.3969/j.issn.1674-8034.2011.03.009.

[1]
Lain WW, Poon WS, Met reweli C. Diffusion MR Imaging in Glioma: Does It Have any Role in the Pre-operation Determination of Grading of Glioma. Clin Radiol, 2002, 57(2): 219-221.
[2]
Takahara T, Imai Y, Yamashita T, et al. Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. Radiat Med, 2004, 22(4): 275-282.
[3]
Barceló J, Vilanova JC, Riera E, et al. Diffusion-weighted whole-body MRI (virtual PET) in screening for osseous metastases. Radiologia, 2007, 49(6): 407-415.
[4]
Engelhard K, Hollenbach HP, Wohlfart K, et al. Comparison of whole-body MRI with automatic moving table technique and bone scintigraphy for screening for bone metastases in patients with breast cancer. Eur Radiol, 2004, 14(1): 99-105.
[5]
Mckinney AM, Reichert P, Short J, et al. Metachronous, multicentric giant cell tumor of the sphenoid bone with histologic, CT, MR imaging and position-emission tomography/CT correlation. AJNR Am J Neuroradiol, 2006, 27(10): 2199-2201.
[6]
徐贤,马林,张金山,等.全身MR扩散加权成像与骨扫描探测骨转移灶的初步对比研究.中华放射学杂志, 2008, 42(6): 636-640.
[7]
Mürtz P, Krautmacher C, Träber F, et al. Diffusion-weighted wholebody MR imaging with background body signal suppression: a feasibility study at 3.0 Tesla. Eur Radiol, 2007, 17(12): 3031-3037.
[8]
Komori T, Narabayashi I, Matsumura K, et al. 2-[Fluorine-18]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography versus whole-body diffusion-weighted MRI for detection of malignant lesions: initial experience. Ann Nucl Med, 2007, 21(4): 209-215.
[9]
顾太富,肖新兰,尹建华,等.应用MR全身扩散加权成像寻找转移瘤原发灶的初步研究.中华放射学杂志, 2008, 42(12): 1279-1282.
[10]
余小多,林蒙,胡满仓,等. 3.0 T磁共振扩散加权成像对肾上腺原发肿瘤的诊断价值.磁共振成像, 2010, 1(5): 366-370.
[11]
徐贤,张金山,马林,等. 3.0 T磁共振全身扩散加权成像的正常表现和初步临床研究.中国医学影像技术, 2007, 3(6): 793-796.

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