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• Clinical Article •
Prelimary study of lumbar intertebral disc degeneration with magnetic resonance spectroscopy, T2 relaxation times and apparent diffusion coefficient
FANG Yuan  LIU Lan-xiang  LI Jing-long  LIU De-feng  CUI Yu-jie  HUANG Song-tao  WANG Zhan-qiu 

DOI:10.3969/j.issn.1674-8034.2011.04.008.


[Abstract] Objective: To explore the value of T2 relaxation time, magnetic resonance spectroscopy (MRS) and apparent diffusion coefficient (ADC) in the lumbar intervertebral disc degeneration.Materials and Methods: Comparison of ADC values, MRSRATIO and T2 relaxation times in 177 discs was performed at different anatomic levels and different Pfirrmann grades in 40 patients.Results: The T2 relaxation times and ADC values were significantly correlated with Pfirrmann grades in different discs, but not in different anatomic levels. ADC values and T2 relaxation time were not correlated with different anatomic levels.Conclusion: ADC values and T2 relaxation time of the lumber intervertebral discs were correlated with increasing Pfirrmann grade. The results of this study support the feasibility of quantitatively assessing spinal degeneration. The values of the MRSRATIO in lumbar intervertebral disc degeneration will be further studied.
[Keywords] T2 relaxation time；Apparent diffusion coefficient；Magnetic resonance spectroscopy

FANG Yuan Department of MR, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China

LIU Lan-xiang* Department of MR, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China

LI Jing-long Department of MR, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China

LIU De-feng Department of MR, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China

CUI Yu-jie Department of MR, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China

HUANG Song-tao Department of MR, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China

WANG Zhan-qiu Department of MR, the First Hospital of Qinhuangdao, Hebei Province, Qinhuangdao 066000, China

*Correspondence to: Liu LX, E-mail: liulanxiang66@sina.com

Conflicts of interest   None.

Received  2010-10-18
Accepted  2011-03-08
DOI: 10.3969/j.issn.1674-8034.2011.04.008
DOI:10.3969/j.issn.1674-8034.2011.04.008.

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