Share：
Share this content in WeChat
X
[Chinese][PDF]130390
• Clinical Article •
Thickened gallbladder wall on MR imaging in patients with liver cirrhotic infected by hepatitis B: correlation with clinical and laboratory results
QI Shi  LI Hong-jun  ZHAO Da-wei 

DOI:10.3969/j.issn.1674-8034.2011.06.003.


[Abstract] Objective: To explore the correlative factors with thickened gallbladder wall in patients with liver cirrhosis caused by hepatitis B.Materials and Methods: The thickness of gallbladder wall, the diameter of portal vein, splenic vein, and superior mesenteric vein were measured on MRI with the laboratory results and virus replication collected. After divided into 2 groups with a threshold of 3 mm in gallbladder wall, the data were compared.Results: The 2 group showed significant difference in serum albumin (P=0.004)and Child-pugh grading(P=0.002), with no difference in total bilirubin (P=0.066), total bile acids (P=0.841), virus replication (P=0.352), or diameter of portal vein (P=0.917), splenic vein (P=0.230), and superior mesenteric vein (P=0.322).Conclusions: The thickness of gallbladder wall in patients with liver cirrhosis infected by hepatitis B maybe associated with serum albumin level and Child-pugh grading. It maybe not correlative with total bilirubin, total bile acids, virus replication, diameter of portal vein, splenic vein and superior mesenteric vein.
[Keywords] Magnetic resonance imaging；Hepatitis, B virus；Liver cirrhosis；Gallbladder wall thickening；Laboratory data

QI Shi Department of Radiology, Capital Medical University, Beijing You'an Hospital, Beijing 100069, China

LI Hong-jun* Department of Radiology, Capital Medical University, Beijing You'an Hospital, Beijing 100069, China

ZHAO Da-wei Department of Radiology, Capital Medical University, Beijing You'an Hospital, Beijing 100069, China

*Correspondence to: Li HJ, E-mail: lihongjun00113@126.com

Conflicts of interest   None.

Received  2011-09-30
Accepted  2011-11-09
DOI: 10.3969/j.issn.1674-8034.2011.06.003
DOI:10.3969/j.issn.1674-8034.2011.06.003.

[1]
Van Breda Vriesman AC, Engelbrecht MR, Smithuis RH，et al. Diffuse gallbladder wall thickening: differential diagnosis. AJR Am J Roentgenol, 2007, 188(2):495-501.
[2]
Basra S, Anand BS. Definition, epidemiology and magnitude of alcoholic hepatitis. World J Hepatol, 2011,3(5):108-113.
[3]
Bota S, Sporea I, Popescu A, et al. Response to standard of care antiviral treatment in patients with HCV liver cirrhosis - a systematic review. J Gastrointestin Liver Dis, 2011,20(3):293-298.
[4]
Chazouillères O. Primary biliary cirrhosis--autoimmune hepatitis overlap syndrome: middle age? Gastroenterol Clin Biol, 2007, 31(1):7-9.
[5]
Morrin MM, Pedrosa I, Rofsky NM. Magnetic resonance imaging for disorders of liver vasculature. Top Magn Reson Imaging, 2002, 13(3):177-190.
[6]
Lu ZY, Zhong NS, Xie Y, et al. Internal Medicine. 7th Edition. BeiJing: People' s Medical Publishing House, 2008:453.
[7]
Acalovschi M, Dumitrascu DL, Nicoara CD. Gallbladder contractility in liver cirrhosis: comparative study in patients with and without gallbladder stones. Dig Dis Sci, 2004, 49(1):17-24.
[8]
Suk KT, Kim CH, Baik SK, et al. Gallbladder wall thickening in patients with acute hepatitis. J Clin Ultrasound, 2009, 37(3):144-148.
[9]
Acalovschi M, Dumitrascu DL, Nicoara CD. Gallbladder contractility in liver cirrhosis: comparative study in patients with and without gallbladder stones. Dig Dis Sci, 2004, 49(1):17-24.
[10]
Jung SE, Lee JM, Lee K, et al. Gallbladder wall thickening: MR imaging and pathologic correlation with emphasison layered pattern. Eur Radiol, 2005, 15(4):694-701.
[11]
Son JY, Kim YJ, Park HS, et al. Diffuse gallbladder wall thickening on computed tomography in patients with liver cirrhosis: correlation with clinical and laboratory variables. J Comput Assist Tomogr, 2011, 35(5):535-538.
[12]
Brogna A, Bucceri AM, Catalano F, et al. Ultrasound demonstration of gallbladder wall thickening as a method to differentiate cirrhotic ascites from other ascites. Invest Radiol, 1996, 31(2):80-83.
[13]
Smith AD, Veniero JC. Gd-EOB-DTPA as a functional MR cholangiography contrast agent: imaging gallbladder filling in patients with and without hepatobiliary dysfunction. J Comput Assist Tomogr, 2011, 35(4): 439-445.
[14]
Bini EJ, McGready J. Prevalence of gallbladder disease among persons with hepatitis C virus infection in the United States. Hepatology, 2005,41(5):1029-1036.
[15]
Wang TF, Hwang SJ, Lee EY, et al. Gall-bladder wall thickening in patients with liver cirrhosis. J Gastroenterol Hepatol, 1997, 12(6):445-449.

PREV Detection of focal liver lesions: comparison of DWI and BLADE-T2-SPAIR sequence
NEXT Preliminary study of MR diffusion weighted imaging in evaluating the degree of liver cirrhosis
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn