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• Clinical Article •
Preliminary study of MR diffusion weighted imaging in evaluating the degree of liver cirrhosis
SHI Dong-li  LI Hong-jun 

DOI:10.3969/j.issn.1674-8034.2011.06.004.


[Abstract] Objective: To investigate the value of MR diffusion weighted imaging (DWI) in patients with liver cirrhosis.Materials and Methods: Ninety-five cases (35 healthy volunteers and 60 patients with liver cirrhosis) were recruited with their apparent diffusion coefficients (ADC) of liver analyzed. According to liver Child-Pugh classification, 60 patients with liver cirrhosis were classified into group AB (28 cases) and group C (32 cases) with their ADC measured and compared intra-group and with that of the volunteers.Results: The ADC values of the control group, group AB and group C were (1.28±0.14)×10-3 mm2/s, (1.18±0.17)×10-3 mm2/s, and (0.91±0.34)×10-3 mm2/s, respectively. The difference was significant between group C and group AB and group C and control group (P=0.000, P=0.000), respectively. There was no statistical significance between group AB and control group (P=0.069).Conclusions: The value of ADC decreased as the aggravation of the hepatic cirrhosis. To some extent, the ADC value may reflect the degree of liver cirrhosis.
[Keywords] Magnetic resonance imaging；Live cirrhosis；Diffusion weighted imaging；Child-Pugh classification

SHI Dong-li Department of Radiology, Capital Medical University, Beijing You'an Hospital, Beijing 100069, China

LI Hong-jun* Department of Radiology, Capital Medical University, Beijing You'an Hospital, Beijing 100069, China

*Correspondence to: Li HJ, E-mail: lihongjun00113@126.com

Conflicts of interest   None.

Received  2011-09-30
Accepted  2011-11-09
DOI: 10.3969/j.issn.1674-8034.2011.06.004
DOI:10.3969/j.issn.1674-8034.2011.06.004.

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