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• Clinical Article •
Study of magnetic resonance diffusion tensor imaging in diabetic optic neuropathy
TIAN Qin  SHI Da-peng  GUO Hui-li  WANG Mei-yun 

DOI:10.3969/j.issn.1674-8034.2012.01.004.


[Abstract] Objective: To explore the value of magnetic resonance diffusion tensor imaging (MR-DTI) in diabetic optic neuropathy.Materials and Methods: Fifteen patients with bilateral diabetic optic neuropathy and 15 healthy subjects were recruited with optic nerve scann by 3.0 T-MR-DTI. The metrics of fractional anisotropy (FA), mean diffusion coefficient (MD), eigenvalue ∥ (λ∥), and eigenvalue ⊥ (λ⊥) values of diabetic optic nerve fibres were calculated and compared between the 2 groups.Results: FA, MD, λ∥, λ⊥ values of diabetic optic nerve fibres were 0.321±0.090, (1808±431)×10-6 mm2/s, (2393±273)×10-6 mm2/s, (1488±467)×10-6 mm2/s, respectively. They were 0.585±0.020, (935±133)×10-6 mm2/s, (1654±157)×10-6 mm2/s, (1026±492)×10-6 mm2/s in controls, respectively. The MD, λ∥, λ⊥ values were higher in affected nerve fibres (P=0.000), but FA value were lower than control nerve fibres (P=0.000).Conclusion: MR-DTI is useful in detecting diabetes optic neuropathy.
[Keywords] Magnetic resonance imaging；Diffusion tensor imaging；Diabetic optic neuropathy

TIAN Qin The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450003, China

SHI Da-peng * Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China

GUO Hui-li Funds Medicine, Henan Institute of Ophthalmology, Henan Provincial People's Hospital, Zhengzhou 450003, China

WANG Mei-yun Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China

*Correspondence to: Shi DP, E-mail: cjr.shidapeng@vip.163.com

Conflicts of interest   None.

Received  2011-11-14
Accepted  2011-12-30
DOI: 10.3969/j.issn.1674-8034.2012.01.004
DOI:10.3969/j.issn.1674-8034.2012.01.004.

[1]
王君婷，郝友娟. 糖尿病视神经病变的FFA及VEP分析.实用医技杂志, 2008, 15(8): 957-959.
[2]
宛四海，张雪林，孙鑫, 等. 正常成人视放射的磁共振扩散张量成像和扩散张量纤维束成像研究. 南方医科大学学报, 2008, 28(3): 396-398.
[3]
Ai-Shafai LS, Mikulis DJ. Diffusion MR imaging in a case of acute ischemic optic neuropathy. Neuroradiology, 2006, 27(2): 255-257.
[4]
Wang Meiyun, Dapeng Shi. Diffusion tensor imaging of optic nerve in anterior ischemic optic neuropathy at 3.0 T. AJNR Am J Neuroradiol, 2011, 32(7): 1188-1194.
[5]
梁军，滕克禹，傅特, 等. 糖尿病性视神经病变的临床特征. 齐鲁医学杂志, 2009, 24(6): 546-547.
[6]
李漫丽，张小猛，王艳丽, 等. 糖尿病性视神经病变的FFA诊断价值. 中国实验诊断学, 2007, 11(2): 217-219.
[7]
何宇，丁俭. 糖尿病导致视路神经元病变的研究进展. 国际眼科杂志, 2010, 4(10): 713-714.
[8]
高丽凤，黄明明，雷皓. 糖尿病大鼠视神经病变方向性扩散加权MRI表现. 波谱学杂志, 2009, 26(4): 485-491.
[9]
Naismith RT, Xu J, Tutlam NT, et al. Radial diffusivity in remote optic neuritis discriminates visual outcomes. Neurology, 2010, 74(2): 1702-1710.
[10]
张海捷，张雪林，文戈, 等. 青光眼视通路的磁共振扩散张量成像研究进展. 国际医学放射学杂志, 2011, 34(2): 135-137.
[11]
Dasenbrock HH, Smith SA, Ozturk A, et al. Diffusion tensor imaging of the optic tracts in multiple sclerosis: association with retinal thinning and visual disability. J Neuroimaging, 2011, 21(2): e41-49.
[12]
Moseley M. Diffusion tensor imaging and aging-a review. NMR Biomed, 2002, 15(7-8): 553-560.

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