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• Clinical Article •
Study of magnetic resonance diffusion tensor imaging in diabetic optic neuropathy
TIAN Qin  SHI Da-peng  GUO Hui-li  WANG Mei-yun 

DOI:10.3969/j.issn.1674-8034.2012.01.004.


[Abstract] Objective: To explore the value of magnetic resonance diffusion tensor imaging (MR-DTI) in diabetic optic neuropathy.Materials and Methods: Fifteen patients with bilateral diabetic optic neuropathy and 15 healthy subjects were recruited with optic nerve scann by 3.0 T-MR-DTI. The metrics of fractional anisotropy (FA), mean diffusion coefficient (MD), eigenvalue ∥ (λ∥), and eigenvalue ⊥ (λ⊥) values of diabetic optic nerve fibres were calculated and compared between the 2 groups.Results: FA, MD, λ∥, λ⊥ values of diabetic optic nerve fibres were 0.321±0.090, (1808±431)×10-6 mm2/s, (2393±273)×10-6 mm2/s, (1488±467)×10-6 mm2/s, respectively. They were 0.585±0.020, (935±133)×10-6 mm2/s, (1654±157)×10-6 mm2/s, (1026±492)×10-6 mm2/s in controls, respectively. The MD, λ∥, λ⊥ values were higher in affected nerve fibres (P=0.000), but FA value were lower than control nerve fibres (P=0.000).Conclusion: MR-DTI is useful in detecting diabetes optic neuropathy.
[Keywords] Magnetic resonance imaging；Diffusion tensor imaging；Diabetic optic neuropathy

TIAN Qin The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450003, China

SHI Da-peng * Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China

GUO Hui-li Funds Medicine, Henan Institute of Ophthalmology, Henan Provincial People's Hospital, Zhengzhou 450003, China

WANG Mei-yun Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China

*Correspondence to: Shi DP, E-mail: cjr.shidapeng@vip.163.com

Conflicts of interest   None.

Received  2011-11-14
Accepted  2011-12-30
DOI: 10.3969/j.issn.1674-8034.2012.01.004
DOI:10.3969/j.issn.1674-8034.2012.01.004.

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