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• Clinical Article •
Comparative study of MRI characteristics between posterior reversible encephalopathy syndrome and MELAS syndrome
TANG Qun-feng  WU Li-yuan  CHEN Hong-wei  XUE Yu-xi  CHENG Wei-jing  XUE Jing  SHEN Jun-kang 

DOI:10.3969/j.issn.1674-8034.2012.01.007.


[Abstract] Objective: To compare the MRI characteristics of posterior reversible encephalopathy syndrome with that of MELAS syndrome.Materials and Methods: Twenty-one patients with PRES and 6 patients with MELAS syndrome were recruited. MRI findings, including the location, signal intensity, and functional characteristics, were retrospectively analyzed.Results: Lesions in the subcortical white matter were found in 21 patients with PRES, and involved cortex in 13 patients. Lesions located in the cortex and subcortical were revealed in 6 patients with MELAS. On DWI, low signal intensity was revealed in 19 patients with PRES; high signal intensity was shown in acute MELAS with isointensity in remission. Decreased cerebral blood volume (CBF) was found in 2 cases of PRES. Increased CBF in 2 cases of MELAS syndrome.Conclusion: Detailed MRI analysis is helpful for the differentiation of PRES and MELAS syndrome.
[Keywords] Posterior reversible encephalopathy syndrome；MELAS syndrome；Magnetic resonance imaging；Comparative study

TANG Qun-feng Department of Radiology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi 214023, China

WU Li-yuan Department of Radiology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi 214023, China

CHEN Hong-wei * Department of Radiology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi 214023, China

XUE Yu-xi Department of Neurology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi 214023, China

CHENG Wei-jing Department of Neurology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi 214023, China

XUE Jing Department of Radiology, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi 214023, China

SHEN Jun-kang Department of Radiology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China

*Correspondence to: Chen HW, E-mail: chw6312@163.com

Conflicts of interest   None.

Received  2011-12-04
Accepted  2012-01-04
DOI: 10.3969/j.issn.1674-8034.2012.01.007
DOI:10.3969/j.issn.1674-8034.2012.01.007.

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