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• Clinical Article •
MRI diagnosis of different levels of oligodendrogliomas
ZHAO Jun  ZHOU Jun-lin  ZHANG Jing 

DOI:10.3969/j.issn.1674-8034.2012.01.008.


[Abstract] Objective: To explore the imaging features in two types of oligodendrogliomas and their histopathological manifestations for better clinical differential diagnosis and treatment guidance.Materials and Methods: We retrospectively examined MRI findings and their histologic correlations of total 59 oligodendroglioma cases diagnosed with both low grade and anaplastic oligodendroglial tumor.Results: There were 37 low grade (WHO Ⅱ grade) and 22 anaplastic (WHO III grade) oligodendrogliomas in this study. Among 37 low grade (WHO Ⅱ grade) cases, the tumor was mostly seen in gray-white matter junction of parietal lobe; 34 cases had blurred margin and 3 cases had well-demarcated margin; on T1-weighted images, the tumor showed hypointense in 33 cases and isointense in 4 cases, on T2-weighted images, the tumor showed hyperintensities on T2-weighted images in 37 cases with mild tumoral enhancement in 30 cases and heterogeneous enhancement in 7 cases; there was other pathological changes such ascalcification (n=32), cystic degeneration (n=7), hemorrhage (n=8), peritumoral edema (n=5). In contrast, among 22 anaplastic oligodendrogliomas (WHO Ⅲ grade), the tumor was mostly seen in the gray-white matter junction of temporal cortex, 21 cases had clear boundary and 1 case with poorly-defined boundary, the tumor showed hypointensities on T1-weighted images in 19 cases and isointensities in 3 cases, the tumor showed hyperintensities on T2-weighted images in 19 cases mild enhancement in 5 cases and significant enhancement in 17 cases, other pathologic findings including cystic necrosis (n=12), hemorrhage (n=9), and peritumoral edema (n=22).Conclusion: We have described the MRI features such as cystic necrosis, hemorrhage, edema, and enhancement that are useful in differentiating the two types of oligodendrogliomas.
[Keywords] Oligodendrogliomas；Pathological grade；Magnetic resonance imaging

ZHAO Jun Center of Imaging Diagnosis, Second Hospital of Lanzhou University, Gansu Lanzhou 730030, China

ZHOU Jun-lin * Center of Imaging Diagnosis, Second Hospital of Lanzhou University, Gansu Lanzhou 730030, China

ZHANG Jing Center of Imaging Diagnosis, Second Hospital of Lanzhou University, Gansu Lanzhou 730030, China

*Correspondence to: Zhou JL, E-mail: zjl601@163.com

Conflicts of interest   None.

Received  2011-11-30
Accepted  2011-01-04
DOI: 10.3969/j.issn.1674-8034.2012.01.008
DOI:10.3969/j.issn.1674-8034.2012.01.008.

[1]
Louis DN, Ohgaki H, Wiestler OD, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol, 2007, 114(2): 97-109.
[2]
Cha S, Tihan T, Crawford F, et al. Differentiation of lowgrade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR Imaging. AJNR Am J Neuroradiol, 2005, 26(2): 266-273.
[3]
沈剑敏，耿道影，沈天真. 脑致痫病变的CT和MRI征象分析. 中国医学计算机成像杂志, 2003, 9(2): 87-92.
[4]
张福林，汪寅，陈宏, 等. 胶质瘤的WHO新分类病理诊断:附1498例统计分析. 中国神经肿瘤杂志, 2003, 1(3): 140-143.
[5]
Ino Y, Betensky RA, Zlatescu MC,et al.Molecular subtypes of anaplastic oligodendroglioma: imp-lications for patient management at diagnosis. Clin Cancer Res, 2001, 7(4):839-845.
[6]
钱银锋，殷敏敏，余永强. 扩散加权成像在低级别胶质瘤的鉴别诊断价值. 磁共振成像, 2010, 1(1): 19-22.
[7]
陈敏，陈涓. 对胚胎发育不良性神经上皮肿瘤的认识. 中国医学影像技术, 2009, 25(3): 512-514.
[8]
张冰，朱斌. DWI在胶质瘤与单发转移瘤及其瘤周水肿中的诊断价值. 中国医学计算机成像杂志, 2006, 12(2): 80-83.
[9]
王廷昱，史克珊，梁其州, 等. 高级别胶质瘤与单发转移瘤的增强后多体素1H-MRS鉴别. 中国临床医学影像杂志, 2008, 19(12): 842-845.
[10]
费小瑞，牛朝诗，王昌新, 等. MR扩散张量成像在评价胶质瘤恶性程度中的作用. 中华放射学杂志, 2009, 43(4): 343-346.

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