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• Clinical Article •
Estimation of DWI and DCE-MRI in the small mass lesions of the breast on MR imaging at 3.0 T
HE Zhi-yan  Mangroo Ateelesh  LI Zhi-yu  YAO Ge-hong  LI Kang-an 

DOI:10.3969/j.issn.1674-8034.2012.02.006.


[Abstract] Objective: To assess the DWI and DCE-MRI in small mass lesions of the breast on MR imaging at 3.0 T.Materials and Methods: A retrospective study was conducted on 62 patients who underwent DWI and DCE-MRI as part of the clinical breast MRI protocol. Patients included in the study had breast lesions with a maximum length of 10mm as the long axis of the lesion on MR imaging.Results: The combined MRI protocol thus exhibited a sensitivity of 100% and a specificity of 75.9%. The ADC values were significantly lower in malignant lesions compared to their benign counterparts. ROC analysis revealed that the threshold value for ADC to distinguish between benign and malignant lesions is 1.11×10-3 mm2/s. Kinetic curve analyses revealed that type II and type III curves should be considered indicative of malignancy.Conclusions: The study demonstrates that DWI and DCE-MRI protocol is easy to carry out and assess. ADC values obtained from DWI can be used to distinguish between benign and malignant breast tumours. This MRI protocol has good sensitivity and specificity. Moreover kinetic curves obtained by DCE-MRI, provide a fairly accurate differentiation between benign and malignant tumours.
[Keywords] Magnetic resonance imaging；DWI；ADC；DCE-MRI；Breast lesions

HE Zhi-yan * Department of Radiology, Shanghai First People’s Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200080, China

Mangroo Ateelesh Department of Radiology, Shanghai Tongji Hospital Affiliated to Medical College of Shanghai Tongji University, Shanghai 200065, China

LI Zhi-yu Department of Radiology, Shanghai First People’s Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200080, China

YAO Ge-hong Department of Radiology, Shanghai First People’s Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200080, China

LI Kang-an Department of Radiology, Shanghai First People’s Hospital Affiliated to Medical College of Shanghai Jiaotong University, Shanghai 200080, China

*Correspondence to: He ZY, E-mail: zhiyan85@hotmail.com

Conflicts of interest   None.

Received  2012-02-05
Accepted  2012-03-05
DOI: 10.3969/j.issn.1674-8034.2012.02.006
DOI:10.3969/j.issn.1674-8034.2012.02.006.

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