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Review
Research progress on proton magnetic resonance spectroscopic imaging for monitoring response of neoadjuvant chemotherapy in breast cancer
ZHANG Ren-zhi  ZHOU Chun-wu 

DOI:10.3969/j.issn.1674-8034.2012.02.013.


[Abstract] MR multi-functional imaging techniques, such as MR perfusion weighted imaging, diffusion weighted imaging and spectroscopic imaging, have a important value in breast cancer diagnosis, differential diagnosis and monitoring therapeutic effect of neoadjuvant chemotherapy for breast cancer. This paper is devoted to reviewing the proton-magnetic resonance spectroscopic (1HMRS ) imaging techniques. The basic principle of 1HMRS, commonly used positioning technology and spectral line postprocessing are intruoduced essentially. Present status and progress of the application on 1HMRS in breast cancer diagnosis, differential diagnosis and monitoring therapeutic effect of neoadjuvant chemotherapy for breast cancer are introduced in detail.
[Keywords] Magnetic resonance imaging;Magnetic resonance spectroscopy;Breast cancer;Neoadjuvant chemotherapy

ZHANG Ren-zhi Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China

ZHOU Chun-wu * Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China

*Correspondence to: Zhou CW, cjr.zhouchunwu@vip.163.com

Conflicts of interest   None.

Received  2011-02-24
Accepted  2012-01-04
DOI: 10.3969/j.issn.1674-8034.2012.02.013
DOI:10.3969/j.issn.1674-8034.2012.02.013.

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