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• Clinical Article •
Comparative study on localization of motor cortex of patients with brain tumors by rs-fMRI and task-based fMRI
NIU Chen  ZHANG Ming  LIN Pan  MIN Zhi-Gang  GAO Lei  Wang Mao-De  JIN Chen-wang  WANG Yuan  ZHU Chao  LIU Xin  LIU Li-hua 

DOI:10.3969/j.issn.1674-8034.2012.03.003.


[Abstract] Objective: To evaluate whether rs-fMRI is appropriate and robust for mapping motor cortex in presurgical planning, by comparing the rs-fMRI and task-based fMRI in mapping motor cortex of brain tumors.Materials and Methods: Twelve patients with brain tumors were selected. Their fMRI dataset was analyzed by FMRIB Software Library Multivariate Exploratory Linear Optimized Decomposition into Independent Components (FSL MELODIC ICA) software (www.fmrib.ox.ac.uk/fsl).Results: The experimental results showed that the motor activation mappings from rs-fMRI are quite similar to those the task-based fMRI in the patients with tumors far from motor cortex activation (patient 1, 3, 7, 8, 11). However, in each of the patients with tumor around motor cortex (patient 2, 4, 5, 6, 9, 10, 12), the spatial distribution of motor cortex activation from the rs-fMRI does not match the distribution from the task-based fMRI well.Conclusion: Based on our experimental results, we find that the combination of rs-fMRI and task-based fMRI should be treated as a complementary approach to assessing the sensorimotor area in patients with brain tumors, which cannot be performed by rs-fMRI alone.
[Keywords] Brain neoplasms；Magnetic resonance imaging；Motor cortex

NIU Chen Imaging Center, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

ZHANG Ming * Imaging Center, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

LIN Pan Institute of Biomedical Engineering, Key Laboratory of Ministry of Education of Biomedical Information Engineering, Xi’an Jiaotong University, Xi’an 710049, China

MIN Zhi-Gang Imaging Center, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

GAO Lei Imaging Center, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

Wang Mao-De Neurosurgery, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

JIN Chen-wang Imaging Center, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

WANG Yuan Imaging Center, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

ZHU Chao Neurosurgery, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

LIU Xin Institute of Biomedical Engineering, Key Laboratory of Ministry of Education of Biomedical Information Engineering, Xi’an Jiaotong University, Xi’an 710049, China

LIU Li-hua Imaging Center, the First Hospital of Xi’an Jiaotong University, Xi’an 710061, China

*Correspondence to: Zhang M, E-mail: zmmri@163.com

Conflicts of interest   None.

Received  2011-12-16
Accepted  2012-02-10
DOI: 10.3969/j.issn.1674-8034.2012.03.003
DOI:10.3969/j.issn.1674-8034.2012.03.003.

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