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• Clinical Article •
Correlation investigate between grade of intratumoral susceptibility signals and relative quantitative of 1H-MRS in patients with brain astrocytic tumours
LIN Qi  ZHANG Qiang  CHEN Dong-ping  XU Kai-hua  CHEN Jin-yin 

DOI:10.3969/j.issn.1674-8034.2012.03.004.


[Abstract] Objective: To investigate the correlation between the grade of intratumoral susceptibility signals (ITSS) in high-resolution susceptibility-weighted imaging(SWI) and relative quantitative of multi-voxel 1H-MRS, and estimate its value on the grade of brain astrocytic tumours.Materials and Methods: The data of 33 patients with brain astrocytic tumours confirmed by postoperative pathologic were collected. Multi-voxel 1H-MRS calculates respectively the relative quantitative of Choline (Cho)/Creotine (Cr), Cho/N-acetylaspartate (NAA), and analyze with grade of ITSS correlation.Results: The high grade astrocytic tumours of ITSS classification was obviously higher than the low grade gliomas (P<0.01). The high grade astrocytic tumours of Cho/Cr, Cho/NAA relative quantitative ratio was obviously higher than the low grade astrocytic tumours (P<0.01). The higher the grade of ITSS was, the bigger the Cho/Cr, Cho/NAA of relative quantitative ratio was, which showed positive correlation (r=0.763, r=0.741, P<0.01).Conclusion: There is better positive correlation between grade of ITSS and relative quantitative of 1H-MRS in patients with brain astrocytic tumours. The grade of ITSS in brain astrocytic tumours can be used as classification diagnostic index.
[Keywords] Brain；Astrocytic tumour；Susceptibility weighted imaging；Magnetic resonance spectroscopy

LIN Qi * Department of radiology, First Hospital of Longyan of Fujian Medical University, Longyan 364000, China

ZHANG Qiang Department of radiology, First Hospital of Longyan of Fujian Medical University, Longyan 364000, China

CHEN Dong-ping Department of radiology, First Hospital of Longyan of Fujian Medical University, Longyan 364000, China

XU Kai-hua Department of radiology, First Hospital of Longyan of Fujian Medical University, Longyan 364000, China

CHEN Jin-yin Department of radiology, First Hospital of Longyan of Fujian Medical University, Longyan 364000, China

*Correspondence to: Lin Q, E-amil: 2624403530@qq.com

Conflicts of interest   None.

Received  2011-12-28
Accepted  2012-02-20
DOI: 10.3969/j.issn.1674-8034.2012.03.004
DOI:10.3969/j.issn.1674-8034.2012.03.004.

[1]
Park MJ, Kim HS, Jahng GH, et al.Semiquantitative assessment of intratumoural susceptibility signals using non-contrast-enhanced high-field high-resolution susceptibility-weighted in patients with gliomas:comparison with MR perfusion imaging. AJNR Am J Neuroradiol, 2009, 30(7): 1402-1408.
[2]
Mittal S, Wu Z, Neelavalli J, et al. Susceptibility-weighted imaging: technical aspects and clinical applications. Part2. AJNR Am J Neuroradiol, 2009, 30(2): 232-252.
[3]
沈俊林，张辉，刘起旺, 等. 磁敏感加权成像对脑肿瘤诊断价值初探. 磁共振成像, 2010,1 (1): 29-35.
[4]
Haacke EM, Mittal S, Wu Z, et al. Susceptibility-weighted imaging:technical aspects and clinical applications. part 1. AJNR Am J Neuroradiol, 2009, 30(1): 19-30.
[5]
林祺，陈金银，许凯华, 等. 3.0T多体素1H-MRS在颅内病变诊断中的应用价值. 中国CT和MRI杂志, 2011, 9(5): 36-38.
[6]
鱼博浪. 中枢神经系统CT和MR鉴别诊断. 陕西: 陕西科学技术出版社, 2005: 9-11.
[7]
刘影，曾飞雁，王昌新, 等. 星形细胞肿瘤内部微结构与ADC值相关性研究. 磁共振成像, 2011, 2(1): 47-49.
[8]
Pinker SA, Noebauer-Huhmann IM, Starrou I, et al. High-resolution contrast-enhanced, susceptibility-weighted MR imaging at 3T in patients with brain tumors: correlation with positron-emission tomography and histopathologic findings. AJNR Am J Neuroradiol, 2007, 28(7): 1280-1286.

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