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Clinical Article
Analysis of MRI on 12 patients with optic nerve glioma
WEI Xiang  LI Jian-gang  REN Guo-zheng  FAN Cun-lei 

DOI:10.3969/j.issn.1674-8034.2012.03.006.


[Abstract] Objective: To evaluate the diagnosis and the differential diagnosis by MRI on patient with optic nerve glioma.Materials and Methods: The manifestations of MRI were retrospectively analyzed in 12 patients with optic nerve glioma whom confirmed by the operation and pathology.Results: In the shape, it revealed as irregular in 5 cases, fusiformis 3 cases, tortuous 4 cases. The glioma involved the orbit in 11 cases, intracanal segment 8 cases, intraocular segment 1 case, optic chiasm 4 cases, optic tract 1 case. For MRI, the presentations of the tumor revealed as iso-or hypointense signal on T1-weighted images, and iso-or hypointense, or hyperintense signal on T2-weighted images. In the tumor, there was homogeneous signal in 10 cases, and cyst lesions with inhomogenous signal in 2 cases, there was not enhanced in 3 cases, enhanced slightly 6 cases, enhanced obviously 3 cases. Nine patients were undergone dynamic contrast-enhanced MRI and time-signal intensity curve including flat in 3 cases, gentle slope in 4 cases and straight slope in 2 cases.Conclusion: It is typically to reveal the features of location, shape, and extent of optic nerve glioma on MRI. MRI is of great value to make a diagnosis and differential diagnosis on optic nerve glioma.
[Keywords] Optic nerve glioma;Magnetic resonance imaging;Diagnosis

WEI Xiang * Department of Radiology First People’s Hospital of Pingdingshan, Henan province, Pingdingshan 467000, China

LI Jian-gang General Hospital of Coal Industy Group, Pingding-shan, Henan province, Pingdingshan 467000, China

REN Guo-zheng Department of Radiology First People’s Hospital of Pingdingshan, Henan province, Pingdingshan 467000, China

FAN Cun-lei Department of Radiology First People’s Hospital of Pingdingshan, Henan province, Pingdingshan 467000, China

*Correspondence to: Wei X, E-mail: weixiang0604@yahoo.com

Conflicts of interest   None.

Received  2012-02-24
Accepted  2012-04-10
DOI: 10.3969/j.issn.1674-8034.2012.03.006
DOI:10.3969/j.issn.1674-8034.2012.03.006.

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