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Clinical Article
A phase contrast magnetic resonance imaging study of hemodynamics of pulmonary artery in patients with repaired tetralogy of Fallot at 3.0 tesla
LIU Hui  WANG Qiu-shi  LIANG Chang-hong  HUANG Mei-ping  XIE Zhao-feng  ZHENG Jun-hui  TAN Shao-heng 

DOI:10.3969/j.issn.1674-8034.2012.04.007.


[Abstract] Objective: To compare pulmonary reguigitation (PR) measured by 3.0 T PC-MRI with data provided by echocardiography and evaluate the relationship between PR and different operation method.Materials and methods: We studied 42 patients (16 female, 26 male, mean age 18.7 years, range 10—51 years) with surgical correction of TOF who performed cardiac magnetic resonance imaging and echocardiography within a month. The pulmonary regurgitation fraction (PRF) and average negative flow (ANF) were calculated during one cardiac cycle. Spearman rank correlation analysis was performed for comparison of measurement results. For comparison PRF and ANF between RVOT patch and transannular patch, Mann-Whtiney U test was employed.Results: By echocardiography criteria,mild PR was present in 10 cases, moderate PR in 32 cases.while PC-MRI showed mild PR in 10 cases(23.8%), moderete PR in 8 cases(19.0%) and severe PR in 24 cases (57.1%) respectively. The different categories (mild,moderate and severe) of PR measured by PC-MRI had a positive liner correlation with the results measured by echocardiography (rs=0.606, P<0.001). Patients with a transannular patch had a significantly higher PRF and ANF than patients with RVOT patch (U=52.000, P=0.001, U=55.000, P=0.002).Conclusion: The PRF measured by 3.0 T PC-MRI has well correlation with that measured by echocardiography, and PC-MRI can provide adequate quantitative information to estimate PRF. 3.0 T PC-MRI can accurately reflect the difference of pulmonary blood flow causing by RVOT patch and transannular patch.
[Keywords] Magnetic resonance imaging;Tetralogay of Fallot;Pulmonary artery;Echocardiography, Doppler

LIU Hui Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China

WANG Qiu-shi Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China

LIANG Chang-hong * Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China

HUANG Mei-ping Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China

XIE Zhao-feng Department of Pediatric Cardiology, Guangdong Cardiovascular Institute, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China

ZHENG Jun-hui Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China

TAN Shao-heng Department of Radiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China

*Correspondence to: Liang CH, E-mail: cjr.lchh@vip.163.com

Conflicts of interest   None.

Received  2012-03-03
Accepted  2012-04-20
DOI: 10.3969/j.issn.1674-8034.2012.04.007
DOI:10.3969/j.issn.1674-8034.2012.04.007.

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