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The mechanisms of iron abnormal deposition and research progressive in the brains of patients with multiple sclerosis
DU Si-lin  LI Yong-mei 

DOI:10.3969/j.issn.1674-8034.2012.04.012.


[Abstract] Histology has showed iron abnormal deposition in the brains of patients with multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) animals. Iron in the brain can be detected and measured accurately using non-invasive magnetic resonance imaging (MRI). The probable pathogenesis and the related to experimental research on the brain iron abnormal deposition in MS patients and animal experiments are reviewed.
[Keywords] Multiple sclerosis；Encephalomyelitis, experimental autoimmune；Magnetic resonance imaging；Iron；Review literature

DU Si-lin Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

LI Yong-mei * Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

*Correspondence to: Li YM, E-mail: lymzhang70@yahoo.com

Conflicts of interest   None.

Received  2011-05-24
Accepted  2012-06-20
DOI: 10.3969/j.issn.1674-8034.2012.04.012
DOI:10.3969/j.issn.1674-8034.2012.04.012.

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