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• Clinical Article •
Dynamic enhanced MRI in the diagnosis of thyroid disease
YUE Xiu-hui  GAO Xin  TAO Xiao-feng 

DOI:10.3969/j.issn.1674-8034.2012.05.009.


[Abstract] Objective: To analyze the dynamic enhancement features of 42 cases with thyroid lesions.Materials and Methods: Forty-two patients (32 women and 10 men, 28 benign and 14 malignant) were included in this prospectively study. Thyroid lesions were prospectively included and underwent DCE MRI before surgery and biopsy. The time-intensity curve (TIC), maximum enhancement ratio (ERmax) and the maximum rise slope (Slopemax) were generated using post-processing Functool software. The median test (2 independent-samples location test) was analyzed by using statistical software SPSS 12.0.Results: All of the 21 cases with I-type curve (rapid increase) were benign thyroid. In 9 cases of II-type curve (platform type), 7 cases were benign lesions and 2 cases were follicular thyroid cancer. All of the 12 cases with III-type curve (delayed up) were malignant lesions. There were significant difference (χ2=4.66, P=0.03) between Slopemax of thyroid carcinoma (median 0.72%/s) and Slopemax of benign lesions (median 4.58%/s). There were significant difference (χ2=4.66, P=0.03) between ERmax of thyroid carcinoma (median 82.82%) and ERmax of benign lesions (median 57.72%).Conclusion: (1) Dynamic contrast-enhanced MR imaging helps to differentiate benign thyroid lesions from and malignant ones. (2) Thyroid carcinoma shows delayed rise in time-intensity curve with dynamic contrast-enhanced MR imaging. Benign thyroid lesions shows rapid increase in time-intensity curve with dynamic contrast-enhanced MR imaging.
[Keywords] Thyroid neoplasms；Thyroid diseases；Magnetic resonance imaging

YUE Xiu-hui Department of Radiology, Shanghai Changzheng Hospital, Shanghai 200003, China

GAO Xin PET/CT, Chinese people's Liberation Army Hospital No.85, Shanghai 200052, China

TAO Xiao-feng * Department of Radiology, Shanghai Ninth People's Hospital, Shanghai 200011, China

*Correspondence to: Tao XF, E-mail: cjr.taoxiaofeng@vip.163.com

Conflicts of interest   None.

Received  2011-04-17
Accepted  2012-07-01
DOI: 10.3969/j.issn.1674-8034.2012.05.009
DOI:10.3969/j.issn.1674-8034.2012.05.009.

[1]
Kusunoki T, Murata K, Nishida S, et al. Histopathological findings of human thyroid tumors and dynamic MRI. AurisNasus Larynx, 2002, 29(4): 357-360.
[2]
Tunca F, Giles Y, Salmaslioglu A, et al. The preoperative exclusion of thyroid carcinoma in multi-nodular goiter: dynamic contrast-enhanced magnetic resonance imaging versus ultrasonography-guided fine-needle aspiration biopsy. Surgery, 2007, 142(6): 992-1002.
[3]
Frates MC, Benson CB, Doubilet PM, et al. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrin Metab, 2006, 91(9): 3411-3417.
[4]
Yeh MW, Demircan O, Ituarte P, et al. False-negative fine-needle aspiration cytology results delay treatment and adversely affect outcome in patients with thyroid carcinoma. Thyroid, 2004, 14(3): 207-215.
[5]
Kusunoki T, Murata K, Nishida S, et al. Histopathological findings of human thyroid tumors and dynamic MRI. Auris Nasus Larynx, 2002, 29(4): 357-360.
[6]
Tunca F, Giles Y, Salmaslioglu A, et al. The preoperative exclusion of thyroid carcinoma in multi-nodular goiter: dynamic contrast-enhanced magnetic resonance imaging versus ultrasonography-guided fine-needle aspiration biopsy. Surgery, 2007, 142(6): 992-1002.
[7]
Kusunoki T, Murata K, Hosoi H, et al. Malignancies of human thyroid tumors and dynamic magnetic resonance imaging (MRI). Auris Nasus Larynx, 1998, 25(4): 419-424.
[8]
Tezelman S, Giles Y, Tunca F, et al. Diagnostic value of dynamic contrast medium-enhanced magnetic resonance imaging in preoperative detection of thyroid carcinoma. Arch Surg, 2007, 142(11): 1036-1041.
[9]
金蓉，李彦敏，王众. 甲状腺肿瘤的彩色血管能量成像与病理微血管密度的对比研究. 中国临床医学影像杂志, 2006, 17(6): 315-317.
[10]
Ramsden JD. Angiogenesis in the thyroid gland. J Endocrinol, 2000, 166(3): 475-480.
[11]
Giorgadze TA, Baloch ZW, Pasha T, et al.Lymphatic and blood vessel density in the follicular pattern-ed lesions of thyroid. Mod Pathol, 2005, 18(11): 1424-1431.
[12]
De la Torre NG, Buley I, Wass JA, et al. Angiogenesis and lymphangiogenesis in thyroid proliferative lesions: relationship to type and tumour behaviour. Endocr Relat Cancer, 2006, 13(3): 931-944.
[13]
马捷，周晓军，周航波, 等. 淋巴管密度在甲状腺乳头状癌和滤泡癌的表达及意义. 中国肿瘤, 2010, 19(6): 418-422.

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