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• Clinical Article •
Dynamic enhanced MRI in the diagnosis of thyroid disease
YUE Xiu-hui  GAO Xin  TAO Xiao-feng 

DOI:10.3969/j.issn.1674-8034.2012.05.009.


[Abstract] Objective: To analyze the dynamic enhancement features of 42 cases with thyroid lesions.Materials and Methods: Forty-two patients (32 women and 10 men, 28 benign and 14 malignant) were included in this prospectively study. Thyroid lesions were prospectively included and underwent DCE MRI before surgery and biopsy. The time-intensity curve (TIC), maximum enhancement ratio (ERmax) and the maximum rise slope (Slopemax) were generated using post-processing Functool software. The median test (2 independent-samples location test) was analyzed by using statistical software SPSS 12.0.Results: All of the 21 cases with I-type curve (rapid increase) were benign thyroid. In 9 cases of II-type curve (platform type), 7 cases were benign lesions and 2 cases were follicular thyroid cancer. All of the 12 cases with III-type curve (delayed up) were malignant lesions. There were significant difference (χ2=4.66, P=0.03) between Slopemax of thyroid carcinoma (median 0.72%/s) and Slopemax of benign lesions (median 4.58%/s). There were significant difference (χ2=4.66, P=0.03) between ERmax of thyroid carcinoma (median 82.82%) and ERmax of benign lesions (median 57.72%).Conclusion: (1) Dynamic contrast-enhanced MR imaging helps to differentiate benign thyroid lesions from and malignant ones. (2) Thyroid carcinoma shows delayed rise in time-intensity curve with dynamic contrast-enhanced MR imaging. Benign thyroid lesions shows rapid increase in time-intensity curve with dynamic contrast-enhanced MR imaging.
[Keywords] Thyroid neoplasms；Thyroid diseases；Magnetic resonance imaging

YUE Xiu-hui Department of Radiology, Shanghai Changzheng Hospital, Shanghai 200003, China

GAO Xin PET/CT, Chinese people's Liberation Army Hospital No.85, Shanghai 200052, China

TAO Xiao-feng * Department of Radiology, Shanghai Ninth People's Hospital, Shanghai 200011, China

*Correspondence to: Tao XF, E-mail: cjr.taoxiaofeng@vip.163.com

Conflicts of interest   None.

Received  2011-04-17
Accepted  2012-07-01
DOI: 10.3969/j.issn.1674-8034.2012.05.009
DOI:10.3969/j.issn.1674-8034.2012.05.009.

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