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• Clinical Article •
Diagnosis in 3.0 T MRI of infiltrating ductal carcinoma of breast
WEI Wei  HUANG Zhong-kui  LONG Li-ling  PEI Yun  JIANG Mu-liang 

DOI:10.3969/j.issn.1674-8034.2012.06.007.


[Abstract] Objective: To investigate the imaging appearance of infiltrating ductal carcinoma at 3.0 T MRI and improve the diagnosis accuracy of infiltrating ductal carcinoma.Materials and Methods: Imaging data of 65 patients (69 lesions) with infiltrating ductal carcinoma proved by operation or biopsy were retrospectively analyzed. All underwent plain, dynamic contrast-enhanced and DWI scan using 3.0 T MRI. The MRI features analyzed included morphological characteristics, hemodynamic performance, the time-signal intensity curve (TIC) and mean ADC. The ADC values for infiltrating ductal carcinoma and normal breast tissue were compared using paired t test and using the grouping design analysis of variance comparison between three type curve difference between ADC values.Results: Sixty-five cases (69 cases of focal) infiltrating ductal carcinoma were performanced with the mass [58.0% (40/69)] or non-mass-like [42.0% (29/69)], margin irregular, equal [36.2% (25/69)] or low signal intensity [63.8% (44/69)] on T1WI, slightly high [27.5% (19/69)] or high signal intensity [72.5% (50/69)] on T2WI, the DWI is slightly high [49.3% (34/69)] or high signal [50.7% (35/69)], the enhanced scanning mass type was early heterogeneous enhancement, internal septal enhancement, non-mass-like give priority to catheter-like and clustered like, time-signal intensity curve to Ⅱ curve [56.5% (39/69)], Ⅲ curve [37.7% (26/69)] is given priority to. With b=1000 mm2/s, the meanADC values for infiltrating ductal carcinoma [(0.93±0.21)×10-3 mm2/s], still can't think three type curve difference between ADC values with a statistical significance (F=0.182, P=0.834>0.05).Conclusion: Application the 3.0 T MRI dynamic contrast-enhanced and DWI scan, can better show lesions form and the strengthen way, combined with morphology characteristics, hemodynamic performance and function characteristics, help to infiltrating ductal carcinoma of preoperative diagnosis.
[Keywords] Carcinoma, ductal, breast；Diffusion magnetic resonance imaging

WEI Wei Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

HUANG Zhong-kui * Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

LONG Li-ling Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

PEI Yun Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

JIANG Mu-liang Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

*Correspondence to: Huang ZK, E-mail: cjr.hzhk@vip.163.com

Conflicts of interest   None.

Received  2012-07-11
Accepted  2012-09-19
DOI: 10.3969/j.issn.1674-8034.2012.06.007
DOI:10.3969/j.issn.1674-8034.2012.06.007.

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