Share：
Share this content in WeChat
X
[Chinese][PDF]968136
• Clinical Article •
Diagnosis in 3.0 T MRI of infiltrating ductal carcinoma of breast
WEI Wei  HUANG Zhong-kui  LONG Li-ling  PEI Yun  JIANG Mu-liang 

DOI:10.3969/j.issn.1674-8034.2012.06.007.


[Abstract] Objective: To investigate the imaging appearance of infiltrating ductal carcinoma at 3.0 T MRI and improve the diagnosis accuracy of infiltrating ductal carcinoma.Materials and Methods: Imaging data of 65 patients (69 lesions) with infiltrating ductal carcinoma proved by operation or biopsy were retrospectively analyzed. All underwent plain, dynamic contrast-enhanced and DWI scan using 3.0 T MRI. The MRI features analyzed included morphological characteristics, hemodynamic performance, the time-signal intensity curve (TIC) and mean ADC. The ADC values for infiltrating ductal carcinoma and normal breast tissue were compared using paired t test and using the grouping design analysis of variance comparison between three type curve difference between ADC values.Results: Sixty-five cases (69 cases of focal) infiltrating ductal carcinoma were performanced with the mass [58.0% (40/69)] or non-mass-like [42.0% (29/69)], margin irregular, equal [36.2% (25/69)] or low signal intensity [63.8% (44/69)] on T1WI, slightly high [27.5% (19/69)] or high signal intensity [72.5% (50/69)] on T2WI, the DWI is slightly high [49.3% (34/69)] or high signal [50.7% (35/69)], the enhanced scanning mass type was early heterogeneous enhancement, internal septal enhancement, non-mass-like give priority to catheter-like and clustered like, time-signal intensity curve to Ⅱ curve [56.5% (39/69)], Ⅲ curve [37.7% (26/69)] is given priority to. With b=1000 mm2/s, the meanADC values for infiltrating ductal carcinoma [(0.93±0.21)×10-3 mm2/s], still can't think three type curve difference between ADC values with a statistical significance (F=0.182, P=0.834>0.05).Conclusion: Application the 3.0 T MRI dynamic contrast-enhanced and DWI scan, can better show lesions form and the strengthen way, combined with morphology characteristics, hemodynamic performance and function characteristics, help to infiltrating ductal carcinoma of preoperative diagnosis.
[Keywords] Carcinoma, ductal, breast；Diffusion magnetic resonance imaging

WEI Wei Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

HUANG Zhong-kui * Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

LONG Li-ling Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

PEI Yun Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

JIANG Mu-liang Department of Radiology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China

*Correspondence to: Huang ZK, E-mail: cjr.hzhk@vip.163.com

Conflicts of interest   None.

Received  2012-07-11
Accepted  2012-09-19
DOI: 10.3969/j.issn.1674-8034.2012.06.007
DOI:10.3969/j.issn.1674-8034.2012.06.007.

[1]
李坤成，孙泽民，尹建国, 等. 乳腺影像诊断学. 北京: 人民卫生出版社, 2003: 245.
[2]
张静. 乳腺MR影像报告和数据系统(BI-RADS—MRI)的临床应用. 中国医学影像学杂志, 2009, 17(1): 51-53.
[3]
Orel SG, Schnall MD. MR imaging of the breast for the detection diagnosis, and staging of breast cancer. Radiology, 2001, 220(1): 13-30.
[4]
陈敏，欧阳汉，全冠民, 等. 体部磁共振诊断学. 福州: 科学技术出版社, 2010:366-367.
[5]
汪登斌. 乳腺MRI检查最佳序列选择及扫描参数优化.磁共振成像, 2011, 2(3): 177-181.
[6]
龚良庚，程流泉. 乳腺非肿块性浸润性导管癌的MRI诊断. 中国医学影像学杂志, 2011, 19(8): 601-604.
[7]
杨帆，孔祥泉，韩萍, 等. 动态增强减影乳腺磁共振成像研究. 临床放射学杂志, 2001, 20(1): 17-20.
[8]
李晶，薛晓喻，续晋铭. 3D-FLASH序列动态MR增强扫描技术在乳腺疾病中的应用. 实用放射学杂志, 2010, 26(1): 84-90.
[9]
谷爽，苏天昊，靳二虎, 等. 乳腺MRI动态增强扫描Ⅰ型曲线的临床意义. 磁共振成像, 2011, 2(3): 190-194.
[10]
李艳玲，李洁，曹崑, 等. 乳腺癌动态增强MRI特征:非肿块样强化与肿块样强化的比较. 中国医学影像技术, 2010, 26(7): 1258-1261.
[11]
范晓彧，杨军. 乳腺浸润性导管癌的MRI诊断. 放射学实践, 2010, 25(1): 59-62.
[12]
Veltman J, Stoutjesdijk M, Mann R, et al. Contrast-enhanced magnetic resonance imaging of the breast: the value of pharmacokinetic parameters derived from fast dynamic imaging during initial enhancement in classifying lesions. Eur Radial, 2008, 18(6): 1123-1133.
[13]
续晋铭，薛晓瑜，卢晓玲. MR动态增强扫描结合扩散加权成像鉴别乳腺良恶性病变的评价. 中国临床医学影像杂志, 2008, 19(12): 899-902.
[14]
朱萍，王亚非，黄昊, 等. MR扩散加权成像表观扩散系数在乳腺结节病变诊断中的应用价值. 中华放射学杂志, 2011, 45(12): 1117-1121.

PREV Relationships between dynamic contrast-enhanced MRI, and pathological types and immunohistochemical findings of patients in breast cancer
NEXT Comparison study on differentiating active from remissive Crohn,s disease by 3.0 T and 1.0 T MRI
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn