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• Clinical Article •
MRI analysis of temporal lobe epileptogenic tumors
DU Tie-qiao  Zhu Ming-wang  ZHAO Dian-jiang  WANG Li-ning  ZHANG Xu-fei 

DOI:10.3969/j.issn.1674-8034.2013.01.004.


[Abstract] Objective: To observe and analyze relationship among clinical, MRI findings and pathological types of the temporal lobe epileptogenic tumors.Materials and Methods: We retrospectively analyzed clinical data of 39 cases with temporal lobe epileptogenic tumor including age of onset, duration and seizure type of epilepsy, MRI features and pathological type of these tumors.Results: The average onset age of the temporal lobe epilepsy was 9.4 years and 36 patients (92.3%) was under 18 years old. An average epilepsy course was 98.8 months. There were 29 cases (74.4%) with complex partial seizures in the group, including 11 cases (28.2%) associated with generalized tonic-clonic seizures (GTCS) and 2 cases (5.1%) with absence seizures. GTCS and tonic seizures were five cases (12.8%) and 2 cases (5.1%), respectively. Simple partial seizures were 3 cases (7.7%). There were 24 ganglioglioma (61.5%), 5 astrocytoma (12.8%), 3 oligodendroglioma (7.7%), 3 dysembryoplastic neuroepithelial tumor (DNET)(7.7%) and 4 the other types (10.3%) in the group. The tumors were located in the mesial and lateral temporal lobe were 71.8% and 28.2%, respectively. Mesial temporal lobe tumors involving hippocampus (71.4%) was significantly higher than that of the lateral group (9.1%). MRI displayed the tumors as solid-cystic component, mainly solid and mainly cystic lesions were 46.2%, 30.8% and 23.1%, respectively. MRI Enhanced scan shows 25 caes (64.1%) with no enhancement. In addition to DNET located within the cortex with multiple small cystic characteristics, there were no significant difference on MRI manifestation of other tumor types.Conclusion: Temporal lobe tumoral epilepsy was common in children, which was mostly slow-growing tumor involving mesial or lateral cortex of the temporal lobe. Ganglioglioma is most common epileptogenic tumor in our patient group, DNET and low-grade gliomasin also appeared in the temporal lobe epilepsy group. The most common seizure type was complex partial seizures with or without GTCS.
[Keywords] Epilepsy, temporal lobe；Nervous system neoplasms；Magnetic resonance imaging

DU Tie-qiao Department of Radiology, Beijing Sanbo Brain Hospital, The 11th Clinical Hospital of Capital Medical University, Beijing 100093, China

Zhu Ming-wang* Department of Radiology, Beijing Sanbo Brain Hospital, The 11th Clinical Hospital of Capital Medical University, Beijing 100093, China

ZHAO Dian-jiang Department of Radiology, Beijing Sanbo Brain Hospital, The 11th Clinical Hospital of Capital Medical University, Beijing 100093, China

WANG Li-ning Department of Radiology, Beijing Sanbo Brain Hospital, The 11th Clinical Hospital of Capital Medical University, Beijing 100093, China

ZHANG Xu-fei Department of Radiology, Beijing Sanbo Brain Hospital, The 11th Clinical Hospital of Capital Medical University, Beijing 100093, China

*Correspondence to: Zhu MW, E-mail: bjneuroradiology@163.com

Conflicts of interest   None.

Received  2012-10-26
Accepted  2012-11-29
DOI: 10.3969/j.issn.1674-8034.2013.01.004
DOI:10.3969/j.issn.1674-8034.2013.01.004.

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