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• Clinical Article •
Occipital cortex magnetic resonance spectrum in the application value of cerebral concussion
ZHANG Hai-du  SHEN Zhi-wei  KONG Ling-mei  ZHENG Wen-bin 

DOI:10.3969/j.issn.1674-8034.2013.02.005.


[Abstract] Objective: occipital cortex proton magnetic resonance spectrum of cerebral concussion patients with absolute quantification (1H-MRS) study, to investigate the changes of cerebral metabolites of brain concussion.Materials and Methods: The trauma of mild cerebral concussion, accord with the clinical diagnosis of the disease in 36 cases studied, 10 healthy volunteers as control group, routine MRI scan and 1H-MRS examination. The main metabolites observed index is N-acetyl aspartic acid (NAA), choline (Cho), creatine (Cr), absolute concentration of metabolites by LCModel software, NAA, Cr, Cho concentration, and NAA/Cr, the ratio of Cho/Cr.Results: compared with control group, the concentration of brain concussion group NAA, NAA/Cr decreased, the difference was statistically significant (P<0.05), Cho concentration and Cho/Cr ratio increased slightly, no statistical significance.Conclusions: 1H-MRS can reflect the changes of cerebral metabolites in patients with concussion of brain.
[Keywords] Brain concussion；Magnetic resonance spectroscopy

ZHANG Hai-du Department of Radiology, the Second Affiliated of Medical College of Shantou University, Shantou 515041, China

SHEN Zhi-wei Department of Radiology, the Second Affiliated of Medical College of Shantou University, Shantou 515041, China

KONG Ling-mei Department of Radiology, the Second Affiliated of Medical College of Shantou University, Shantou 515041, China

ZHENG Wen-bin* Department of Radiology, the Second Affiliated of Medical College of Shantou University, Shantou 515041, China

*Correspondence to: Zheng WB, E-mail: hwenb@126.com

Conflicts of interest   None.

Received  2013-01-15
Accepted  2013-02-18
DOI: 10.3969/j.issn.1674-8034.2013.02.005
DOI:10.3969/j.issn.1674-8034.2013.02.005.

[1]
Mulhern S, Mcmillan TM. Knowledge and expectation of postconcussion symptoms in the general population. J Psychosom Res, 2006, 61(4): 439-445.
[2]
Blumbergs PC, Scott G, Manavis J, et al. Staining of myloid precursor protein to study axonal damage in mild head injury. Lancet, 2001, 344(8929): 1055-1056.
[3]
Paul AM, Sven ZS, Marinus JP, et al. MR imaging, single photon emission CT, and neurocognitive performance after mild traumatic brain injury. Am J Neuroradiol, 2001, 22(3): 441-449.
[4]
郭绣琴，肖叶玉，沈智威,等.磁共振频谱数据定量后处理技术比较.磁共振成像, 2010, 1(2): 126-129.
[5]
Govindaraju V, Gauger GE, Geoffrey T, et al. Volumetric proton spectroscopic imaging of mild traumatic brain injury. AJNR Am J Neuroradiol, 2004, 25(5): 730-737.
[6]
舒细记，柳威，周红艳,等.脑震荡后综合征大鼠海马的神经损伤及磁共振波谱分析.江汉大学学报自然科学版, 2010, 38(1): 74-78.
[7]
Shutter L, Tong KA, Lee A, et al. Prognostic role of proton magnetic resonance spectroscopy in acute traumatic brain injury. Head Trauma Rehabil, 2006, 21(4): 224-349.
[8]
Hunter JV, Thornton RJ, Wang ZJ, et al. Late proton mr spectroscopy in children after traumatic brain injury: correlation with cognitive outcomes. Neuroradiol, 2005, 26(5): 482-488.
[9]
Frahm J, Bruhn H, Gyngell ML, et al. Localized proton NMR spectroscopy indifferent regions of the human brain invivo：relaxation times and concentration in vivo：relaxation times and concerntration of cerebral metabolites. Magn Reson Med, 1989, 11(7): 47-63.
[10]
Shigemore M, Kikuchi N, Tokutome T, et al. Coexisting diffuse axonal injury (DAI) and outcome of severe head injury. Acta Neurochir Suppl (Wien), 1992, 55(9): 37-39.
[11]
Barbara A, Holshouser, Stephen A, et al. Proton MR spectroscopy after acute central nervous system injury: outcome predictionin neonates, infants, and children. Radiology, 1997, 202(8): 487-496.
[12]
Kreis R, Arcinue E, Ernst T, et al. Hypoxic encephalopathy after near-drowning studied by quantitative 1H-magnetic resonance spectroscopy. J Clin Invest, 1996, 97(12): 1142-1154.
[13]
Auld KL, Ashwal S, Holshouser BA, et al. Proton magnetic resonance spectroscopy in children with acute central nervous system injury. Pediatr Neurol, 1995, 12(5): 323-334.
[14]
Barbara A, Holshouser, Karen A, et al. Proton MR spectroscopic imaging depicts diffuse axonal injury in children with traumatic brain injury. Am J Neuroradiol, 2005, 26(3): 1276-1285.

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