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• Clinical Article •
A comparative study of MRI findings between active and no active lesions in ulcerative colitis patients
CHANG Guo-qing  SUN Hao-ran  ZHAO Xin  WANG Min 

DOI:10.3969/j.issn.1674-8034.2013.02.007.


[Abstract] Objective: To compare MR findings of active lesions and no active lesions in a group of ulcerative colitis (UC) patients, to evaluate the difference between active lesions and no active lesions by MR imaging.Materials and Methods: Total 13 patients with histopathologically confirmed ulcerative colitis enrolled in this retrospective study, including seven active lesions and six no active lesions. The bowel thickness, incidences of bowel wall stratification like "target sign" , mesenteric stranding like "comb sign" and adjacent enlarged lymph nodes were measured, then the time-signal intensity curves (TICs) of diseased bowel after dynamic contrast enhanced MRI (DCE-MRI) were plotted, time to peak (TTP) value and relative enhancement rate (Er) after correction by psoas muscle were calculated, the differences of MR findings between the active and no active lesions were compared statistically.Results: The bowel thickness of active lesions was significantly increased than that of no active lesions [(11.1±3.7) mm versus (5.3±1.2) mm, P<0.1]. There were also significant differences in the incidences of bowel wall stratification like "target sign" and mesenteric stranding like "comb sign" between the two groups (71.4% versus 0, 85.7% versus 0. P<0.01). But there was no significant difference of mesenteric enlarged lymph nodes between active and no active UC (42.9% versus 16.7%. P>0.05). The types of TIC in active group were fast rising and fall slowly, however the type of TIC in no active group was slowly rising. TTP and Er differed significantly between them [(111.4±48.1) s versus (240.0±50.2) s. (166.3±98.8)% versus (49.6±41.6)%. P<0.05].Conclusions: There were differences in bowel thickness, mesenteric stranding like "comb sign" , bowel wall stratification like "target sign" , TTP and Er between active and no active UC.
[Keywords] Magnetic resonance imaging；Colitis, ulcerative；Pathology；Diagnosis, differential

CHANG Guo-qing Department of Radiology, Tianjin Medical University General Hospital, Tianjin 300052, China

SUN Hao-ran* Department of Radiology, Tianjin Medical University General Hospital, Tianjin 300052, China

ZHAO Xin Department of Radiology, Tianjin Medical University General Hospital, Tianjin 300052, China

WANG Min Department of Radiology, Inner Mongolia Autonomous Region People’s Hospital, Hohhot 010017, China

*Correspondence to: Sun HR, E-mail: sunhaoran2006@hotmail.com

Conflicts of interest   None.

Received  2013-01-06
Accepted  2013-02-28
DOI: 10.3969/j.issn.1674-8034.2013.02.007
DOI:10.3969/j.issn.1674-8034.2013.02.007.

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