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• Clinical Article •
Value of contrast measurement of ESWAN-R2* value in diagnosis of neonatal punctate white matter lesions
REN Hui-peng  ZHANG Lei  REN Zhuan-qin  CHEN Tao  WANG Xiao-hu  LI Jing  LI Li  GOU Xiao-guang 

DOI:10.3969/j.issn.1674-8034.2013.03.008.


[Abstract] Objective: To probe the Value of ESWAN-R2* value in diagnosis of neonatal punctate white matter lesions (PWML).Materials and methods: 22 neonates according with the diagnostic standard of PWML were all performed conventional MRI, DTI, ESWAN examination (10 cases of premature, 12 cases of full-term infants), and 22 cases of normal neonates as controls (10 cases of premature, 12 cases of full-term infants). The neonates of case group and control group were divided into premature group and full-term group respectively. Measure the R2* value of the neonatal PWML lesions, the contralateral side of the lesions, and the same location of lesions in normal neonates, and then compared the values with each other.Results: the R2* value of the lesions, the contralateral side of the lesions, and the same location of lesions in normal neonates of the premature group are as follows: 7.458±2.463, 5.708±2.277, 4.024±0.940, the R2* value of full-term group’s are as follows: 8.609±2.461, 6.621±2.072, 5.250±1.526, the R2* value of the neonatal PWML are higher than the contralateral side of the lesions and the normal neonates, and the differences between lesions and the normal neonates are significant (P<0.05).Conclusion: contrast measurement of ESWAN-R2* value has important value in the diagnosis of neonatal PWML.
[Keywords] Punctate white matter lesions；Magnetic resonance imaging；Hypoxia-ischemia, brain；Infant, newborn

REN Hui-peng Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

ZHANG Lei Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

REN Zhuan-qin* Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

CHEN Tao Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

WANG Xiao-hu Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

LI Jing Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

LI Li Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

GOU Xiao-guang Department of Imaging, Baoji City Central Hospital of shan xi Province, Baoji 721008, China

*Correspondence to: Ren zq, E-mail: renzhuanqin@163.com

Conflicts of interest   None.

Received  2013-03-10
Accepted  2013-04-10
DOI: 10.3969/j.issn.1674-8034.2013.03.008
DOI:10.3969/j.issn.1674-8034.2013.03.008.

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