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• Clinical Article •
T2 mapping of knee cartilage damage at 3.0 T MR imaging
WU Kun-hua  WANG Tian-chao  LIANG Hong  GONG Xia-rong  DAI Min-fang  XIE Xu-hua  ZHANG Hong  Chen Yu-hui  BI Guo-li 

DOI:10.3969/j.issn.1674-8034.2013.03.010.


[Abstract] Objective: To evaluate early knee cartilage damage with T2 mapping at 3.0 T MRI.Materials and methods: T2 mapping of knee cartilage was evaluated quantitatively at a 3.0 T MRI scanner in 100 patients with osteoarthritis, rheumatoid arthritis, cartilage injury respectively and in 100 healthy subjects (group B). T2 value in eleven compartments of knee cartilage (central medial femoral region, posterior medial femoral region, central lateral femoral region, posterior lateral femoral region, anterior medial tibial region, central medial tibial region, posterior medial tibial region, anterior lateral tibial region, central lateral tibial region, posterior lateral tibial region, patella region) were measured respectively in T2 mapping imaging. Statistical differences and the correlation between T2 value and WORMS scores were analyzed.Results: The everage T2 relaxation time for knee cartilage damaged group (group A) and healthy subjects (group B) were (44.39±15.28) ms and (31.70±8.33) ms respectively. T2 values of the former group were significantly higher than those in later group. Significant difference was found between these two groups (P<0.05). T2 values of knee cartilage damaged group were highly correlated with WORMS scores (r=0.405-0.847, P<0.01).Conclusion: T2 mapping imaging can demonstrate early knee articular cartilage damage, and it is of a high clinical value modality for articular cartilage evaluation.
[Keywords] Cartilage, articular；Knee injuries；Magnetic resonance imaging

WU Kun-hua Department of MRI, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

WANG Tian-chao Department of MRI, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

LIANG Hong Department of MRI, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

GONG Xia-rong Department of MRI, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

DAI Min-fang Department of MRI, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

XIE Xu-hua Department of Orthopedic Surgery, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

ZHANG Hong Department of Rheumatoid and Immunology Medicine, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

Chen Yu-hui Department of MRI, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

BI Guo-li Department of MRI, the Affiliated Hospital of Kunming Medical University, Kunming 650032, China

Conflicts of interest   None.

Received  2013-03-07
Accepted  2013-04-19
DOI: 10.3969/j.issn.1674-8034.2013.03.010
DOI:10.3969/j.issn.1674-8034.2013.03.010.

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