Share：
Share this content in WeChat
X
[Chinese][PDF]769106
• Clinical Article •
High-resolution MRI study of middle cerebral artery stenosis rate differences in infarct and TIA patients
XIE Shan-shan  CHENG Jing-liang  ZHANG Yong  KOU Pei-si 

DOI:10.3969/j.issn.1674-8034.2013.06.003.


[Abstract] Objective: To investigate the stenosis rate differences of atherosclerotic middle cerebral artery (MCA) between cerebral infarct and TIA patients with high-resolution magnetic resonance imaging (HR MRI).Materials and Methods: Ninety-one consecutive patients with symptomatic atherosclerotic stenosis at M1 segment of MCA on MRA or DSA were enrolled from April 2011 to April 2013. HRMRI was performed on the target segment by using a 3.0 T MR scanner. Stenosis rate was calculated as vessel area at maximal lumen narrowing/reference vessel area. Diffusion weighted imaging (DWI), T2WI and dark-fluid sequences were performed to make sure if infarct occurred.Results: Seventy-eight patients were included in the final analysis, including 46 patients with infarct, the stenosis of which is 0.72±0.21, and 32 patients with TIA, the stenosis rate 0.72±0.20. The rate difference between patients with infarct and TIA was not statistically significant (t=-0.10, P>0.05).Conclusions: The stenosis rates of M1 segment of MCA in patients with infarct and TIA have no difference, suggesting that the stenosis rate of M1 segment of MCA is not the determining factor of infarction.
[Keywords] Infarction, middle cerebral artery；Ischemic attack, transient；Magnetic resonance imaging

XIE Shan-shan Department of MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

CHENG Jing-liang * Department of MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

ZHANG Yong Department of MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

KOU Pei-si Department of MRI, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

*Correspondence to: Cheng JL, Email: chengjl-2008@163.com

Conflicts of interest   None.

Received  2013-08-27
Accepted  2013-10-10
DOI: 10.3969/j.issn.1674-8034.2013.06.003
DOI:10.3969/j.issn.1674-8034.2013.06.003.

[1]
Wong KS. Global burden of intracranial atherosclerosis. Inter J Stroke, 2006, 1(3): 158-159.
[2]
Wong KS, Li H, Chan YL, et al. Use of transcranial Doppler ultrasound to predict outcome in patients with intracranial large-artery occlusive disease. Stroke, 2000, 31(11): 2641-2647.
[3]
Wong KS, Huang YN, Gao S, et al. Intracranial stenosis in Chinese patients with acute stroke. Neurology, 1998, 50(3): 812-813.
[4]
Yarnykh VL, Yuan C. Multislice double inversion-recovery black-blood imaging with simultaneous slice reinversion. J Magn Reson Imaging, 2003, 17(4): 478-483.
[5]
Xu WH, Li ML, Gao S, et al. In vivo high-resolution MR imaging of symptomatic and asymptomatic middle cerebral artery atherosclerotic stenosis. Atherosclerosis, 2010, 212(2): 507-511.
[6]
Ma N, Jiang WJ, Lou X, et al. Arterial remodeling of advanced basilar atherosclerosis: a 3-tesla MRI study. Neurology, 2010, 75(3): 253-258.
[7]
Underhill HR, Yarnykh VL, Hatsukami TS, et al. Carotid plaque morphology and composition: initial comparison between 1.5-and 3.0 T magnetic field strengths. Radiology, 2008, 248(2): 550-560.
[8]
Wityk RJ, Lehman D, Klag M, et al. Race and sex differences in the distribution of cerebral atherosclerosis. Stroke, 1996, 27(11): 1974-1980.
[9]
Sacco RL, Kargman DE, Gu Q, et al. Race-ethnicity and determinants of intracranial atherosclerotic cerebral infarction: the northern manhattan study. Stroke, 1995, 26(1): 14-20.
[10]
Caplan LR, Gorelick PB, Hier DB. Race, sex and occlusive cerebrovascular disease: a review. Stroke, 1986, 17(4): 648-655.
[11]
De Silva DA, Woon FP, Lee MP, et al. South Asian patients with ischemic stroke: intracranial large arteries are the predominant site of disease. Stroke, 2007, 38(9): 2592-2594.
[12]
Gorelick PB, Wong KS, Bae HJ, et al. Large artery intracranial occlusive disease: a large worldwide burden but a relatively neglected frontier. Stroke, 2008, 39(8): 2396-2399.
[13]
Yoshida K, Narumi O, Chin M, et al. Characterization of carotid atherosclerosis and detection of soft plaque with use of black-blood MR imaging. AJNR Am J Neuroradiol, 2008, 29(5): 868-874.
[14]
李明华，李梅．易损斑块的影像学检查方法．磁共振成像, 2010, 1(6): 411-414.
[15]
Ryu CW, Jahng G, Kim EJ, et al. High resolution wall and lumen MRI of the middle cerebral arteries at 3 Tesla. Cerebrovasc Dis, 2009, 27(5): 433-442.
[16]
高山，黄家星，黄一宁．动脉粥样硬化性大脑中动脉狭窄梗死的发病机制．中华神经科杂志, 2003, 36(2): 155-157.
[17]
李萍，张在人，赵雁鸣，等．多层CT脑灌注成像与CT血管成像诊断颈动脉狭窄性短暂性脑缺血发作．实用放射学杂志, 2008, 25(8): 1079-1082.
[18]
Wong KS, Gao S, Chan YL, et al. Mechanisms of acute cerebral infarctions in patients with middle cerebral artery stenosis:a diffusion-weighted and microemboli monitoring study. Ann Neurol, 2002, 52(1): 74-81.
[19]
Droste D, Dittrich R, Kemeny V, et al. Prevalence and frequency of microembolic signals in 105 patients with extracranial carotid artery occlusive disease. J Neurol Neurosurg Psychiatry, 1999, 67(4): 525-528.
[20]
Wong KS, Gao S, Lam W, et al. A pilot study of microembolic signals in patients with middle cerebral artery stenosis. J Neuroimaging, 2001, 11(2): 137-140.
[21]
苑纯，赵锡海，易损斑块磁共振成像：共识与挑战．磁共振成像, 2010, 1(6): 429-431.

PREV MR enterography with oral isosmotic mannitol
NEXT Study on memory function impairment and structural MRI in posttraumatic stress disorder
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn