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• Clinical Article •
Application value of MR spectroscopy in the peritumoral tissue of brain astrocytic tumours
LIN Qi  HE Yong-hong  TAN Ping-tai  TANG Lang-lang 

DOI:10.3969/j.issn.1674-8034.2014.01.003.


[Abstract] Objective: To discuss metabolic feature in the peritumoral tissue of different ranks brain astrocytic tumours with multi-voxel proton magnetic resonance spectroscopy (1H-MRS), and estimate its application value on of brain astrocytic tumours.Materials and Methods: 82 patients with brain astrocytic tumours confirmed by postoperative pathologic were collected, which were divided into low grade astrocytic tumours (WHO I—II) 32 cases, and high grade astrocytic tumours (WHO III—IV) 50 cases. The semiquantitative and relatively quantitative ratio of metabolic of the parenchyma area,peritumoral tissues area,and area with normal area were measured, and value was set as P<0.05.Results: The relative quantitative ratios of Cho/Cr, Cho/NAA significantly differed in peritumoral tissues area of the high grade astrocytic tumours and the low grade astrocytic tumours (P<0.01), but NAA/Cr had no significant difference (P>0.05).Conclusions: The changes of the MRS quantitative ratio in brain astrocytic tumours peritumoral tissues area reflects the level of different tumor biological behavior, and it has important clinical value in determining the classification of the brain astrocytic tumours and the scope of attack.
[Keywords] Astrocytoma；Brain neoplasms；Magnetic resonance spectroscopy

LIN Qi* First Hospital of Longyan, Hospital of Fujian Medical University, Longyan 364000, China

HE Yong-hong First Hospital of Longyan, Hospital of Fujian Medical University, Longyan 364000, China

TAN Ping-tai First Hospital of Longyan, Hospital of Fujian Medical University, Longyan 364000, China

TANG Lang-lang First Hospital of Longyan, Hospital of Fujian Medical University, Longyan 364000, China

*Correspondence to: Lin Q, E-mail:2624403530@qq.com

Conflicts of interest   None.

Received  2013-10-25
Accepted  2013-12-05
DOI: 10.3969/j.issn.1674-8034.2014.01.003
DOI:10.3969/j.issn.1674-8034.2014.01.003.

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