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Clinical Article
Study of multi-modality MRI on dysplastic nodule with cirrhosis
LI Yun-fang  LI Hong-jun  ZHANG Yan-yan 

DOI:10.3969/j.issn.1674-8034.2014.01.010.


[Abstract] Objective: Study the imaging features of dysplastic nodule (DN) with cirrhosis by multi-modality MRI, to reveal the correlation between DN imaging features and pathological evolution mechanism.Materials and Methods: Fifteen patients with DN confirmed by pathology, laboratory tests, follow-up and several kinds of imaging examination. All patients underwent multi-modality MRI examination.Results: DN lesions showed high signal in T1WI by 80%, showed equal or low signal by 66.7% in T2WI. SNR, CNR value of the DN in T1WI and T2WI showed no obviously different from the liver parenchyma. DWI showed equal or low signal in 80% lesions as cancerous lesions in DN were high signal. All DN lesions were detected in SWI. DN cancerous lesion was slightly high signal in T1WI, with slightly low signal area in it while there was slightly high signal area in the lesion in T2WI. DN cancerous lesion was high signal in DWI. Enhancement time-signal intensity curve of DN showed almost the same with the liver parenchyma, which of cancerous lesions in DN obvious was similar to the curve of HCC. Contrast with the pathological findings, some HGDN could be diagnosed by image features.Conclusions: There was some correlation between DN imaging features and pathological evolution mechanism.
[Keywords] Liver cirrhosis;Magnetic resonance imaging

LI Yun-fang Department of Radiology, Affiliated Beijing You’an Hospital, Capital Medical University, Beijing 100069, China

LI Hong-jun* Department of Radiology, Affiliated Beijing You’an Hospital, Capital Medical University, Beijing 100069, China

ZHANG Yan-yan Department of Radiology, Affiliated Beijing You’an Hospital, Capital Medical University, Beijing 100069, China

*Correspondence to: Li HJ, E-mail: lihongjun00113@126.com

Conflicts of interest   None.

Received  2013-12-05
Accepted  2013-12-25
DOI: 10.3969/j.issn.1674-8034.2014.01.010
DOI:10.3969/j.issn.1674-8034.2014.01.010.

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