Share：
Share this content in WeChat
X
[Chinese][PDF]77665
• Clinical Article •
Dynamic contrast-enhanced MR imaging combined with T2*-weighted first-pass perfusion imaging in diagnosis of breast tumor
ZHAO Jin-li  GUAN Hai-tao  LI Min-da  WU Xian-hua  GU Hong-mei  ZHOU Xue-jun 

DOI:10.3969/j.issn.1674-8034.2014.01.011.


[Abstract] Objective: To evaluate the value of breast T1WI dynamic enhancement scanning combined with T2*-weighted first-pass perfusion imaging in differential diagnosis of benign and malignant breast tumors.Materials and methods: 39 cases of benign or malignant breast tumors verified by pathology underwent T2*-weighted first-pass perfusion imaging and T1WI dynamic enhanced scan. We calculated the reduction rate of maximum signal strength in T2*-weighted first-pass perfusion imaging and the early enhancement rate of dynamic enhanced scan. We also drew the TIC of T2*-weighted first-pass perfusion imaging and T1WI dynamic enhanced scan.Results: There was a statistically significant difference in the reduction rate of the maximum signal strength in T2*-weighted first-pass perfusion imaging of breast neoplasms. When the scale of decrease of maximum signal which arrived 20% be identified as threshold, the sensitivity was 91.7%, specificity was 93.3%, and the accuracy is 92.3%. The difference of early enhancement rate in dynamic enhanced scan of breast neoplasms was not statistically different, but the type of dynamic enhancement curve had statistically significant difference. When the curve was outflow type, it could be defined as malignant standard (sensitivity was 62.5%, specificity was 93.3%, the accuracy was 74.4%). When TIC curve in T1WI dynamic enhanced scan of breast neoplasms was platform type (type II), the type of TIC curve in T2*-weighted first-pass perfusion imaging had statistically significant difference.Conclusions: T1WI dynamic enhanced scan combined with T2*-weighted first-pass perfusion imaging can be help to distinguish benign breast tumors from malignant ones. T2*-weighted first-pass perfusion imaging can improve the accuracy of qualitative diagnosis when TIC curve in T1WI dynamic enhanced scan of breast neoplasms was type II.
[Keywords] Breast neoplasms；Magnetic resonance angiography

ZHAO Jin-li Department of Radiology, Afiliated Hospital of Nantong University, Nantong 226001, China

GUAN Hai-tao the Third People's Hospital of Nantong, Nantong 226001, China

LI Min-da Department of Radiology, Afiliated Hospital of Nantong University, Nantong 226001, China

WU Xian-hua* Department of Radiology, Afiliated Hospital of Nantong University, Nantong 226001, China

GU Hong-mei Department of Radiology, Afiliated Hospital of Nantong University, Nantong 226001, China

ZHOU Xue-jun Department of Radiology, Afiliated Hospital of Nantong University, Nantong 226001, China

*Corresponding author: Wu XH, E-mail: wxh637295@sina.com

Conflicts of interest   None.

Received  2013-10-06
Accepted  2013-12-05
DOI: 10.3969/j.issn.1674-8034.2014.01.011
DOI:10.3969/j.issn.1674-8034.2014.01.011.

[1]
庄晓明，张冰，朱斌,等.磁共振T2*W首过灌注成像在乳腺肿瘤诊断中的应用.中国癌症杂志, 2006, 16(10): 851-854.
[2]
Kvistad KA, Rydland J, Vainio J, et al. Breast lesions: evaluation with dynamic contrast-en hanced T1-weighted MR imaging and with T2*-weighted first-pass perfusion MR imaging. Radiology, 2000, 216(2):545-553.
[3]
Kuhl CK, Schnall MD, Orel SG, et al. Correlation of lesion appearance and histologic findings for the nodes of a breast MR imaging interpretation mode. Radiographics, 1999, 19(1): 79-92.
[4]
Geimaerdt MJ, Hogendoom PC, Bolem JL, et al. Cartilaginous tumors fast contrast-enhancemented MR imaging. Radiology, 2000, 214(2):539-546.
[5]
Sinhu S, Sinha U. Functional magnetic resonance of human breast tumors diffusion and perfusion imaging. Ann N Y Acad Sci, 2002,980(1): 95-115.
[6]
王云兰，王文峰，魏冉,等.乳腺MR灌注时间-信号强度曲线表现及价值研究.临床放射学杂志, 2011, 30(2): 197-201.
[7]
Tozaki M, Fukuda K. High-spatial-resolution MRI of non-masslike breast lesions: interpretation model based on BI-RADS MRI descriptors. AJR Am J Roentgenol, 2006, 187(2): 330-337.
[8]
Kvistad KA, Lundgren S. Differentiating benign and malignant breast lesions with T2*- weighted first-pass perfusion imaging. Acta Radiol, 1999, 40(1): 45-51.
[9]
Zhang B, Zhu B, Li M, et al. Comparative utility of MRI perfusion with MSIDR and DWIBS for the characterization of breast tumors. Acta Radiol, 2012, 53(6): 607-614.
[10]
万芸，陈树良，田铁桥,等.乳腺MR T1WI动态增强与T2*WI首过灌注成像相结合对乳腺良恶性病变的鉴别诊断.临床放射学杂志, 2012, 31(2): 184-187.
[11]
王世威，许茂盛，丁雪委,等.半定量双回波动态对比增强MRI诊断乳腺肿瘤的价值.中华放射学杂志, 2013, 47(8): 695-698.
[12]
Veltman J, Stoutjesdijk M, Mann R, et al. Contrast-enhanced magnetic resonance imaging of the breast: the value of pharmacokinetic parameters derived from fast dynamic imaging during initial enhancement in classifying lesions. Eur Radiol, 2008, 8 (6):1123-1133.
[13]
何之彦，Ateelesh Mangroo，李志宇,等. 3.0 T MR扩散加权和动态增强对乳腺小肿块性病灶的诊断价值.磁共振成像, 2012, 3(2):120-124.
[14]
谷爽，苏天昊，靳二虎,等.乳腺MRI动态增强扫描I型曲线的临床意义.磁共振成像, 2011, 2(3): 190-194.
[15]
Kuhl CK, Mielcareck P, Klaschik S, et al. Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions. Radiology, 1999, 211(1): 101-110.
[16]
Malru S, Wurdinger S, Moriz A, et al. Comparison of written reports of ammography, sonography and magnetic resonance mammography for pre-operative evaluation of breast lesions, with special on magnetic resonance mammography. Breast Cancer Res, 2001, 3(1): 55-60.
[17]
Goto M, Ito H, Akazawa K, et al. Diagnosis of breast tumors by contrast-enhanced MR imaging: comparison between the diagnostic performance of dynamic enhancement patterns and morphologic features. J Magn Reson Imaging, 2007, 25(1): 104-112.
[18]
刘佩芳，尹璐，牛昀.乳腺黏液腺癌MRI表现特征及其与病理对照研究.中华放射学杂志, 2009, 43(5): 470-475.

PREV Study of multi-modality MRI on dysplastic nodule with cirrhosis
NEXT Quantitative assessment of hyperacute ischemic stroke onset time window
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn