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The application of magnetic resonance cell tracing technique in myocardial infarction cell transplantation treatment
CUI Chen  ZHAO Shi-hua 

DOI:10.3969/j.issn.1674-8034.2014.03.015.


[Abstract] Stem cell transplantation has the potential to treat myocardial infarction. MRI is emerging as a robust tool to provide anatomical and functional information of patient with cardiovascular disease, but also plays an important role in tracing graft cells. SPIO is one of the most widely used probes, which can identify the graft site accurately. However, the presence of SPIO cannot guarantee the survival of the stem cells and this limits its use. The MRI reporter gene imaging technique can fill this gap to access the survival information of the grafted cells and help researchers to achieve a higher level of understanding of the fate of the cell.
[Keywords] Magnetic resonance imaging；super paramagnetic iron oxide；Reporter gene imaging

CUI Chen Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital and Cardiovascular Institute, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 10037, China

ZHAO Shi-hua* Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital and Cardiovascular Institute, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 10037, China

*Correspondence to: Zhao SH, E-mail: cjrzhaoshihua2009@163.com

Conflicts of interest   None.

Received  2014-01-20
Accepted  2014-02-26
DOI: 10.3969/j.issn.1674-8034.2014.03.015
DOI:10.3969/j.issn.1674-8034.2014.03.015.

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