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• Clinical Article •
MRI diagnosis of the breast intraductal papilloma
ZHANG Ren-zhi  ZHOU Chun-wu  LI Jing  OUYANG- Han 

DOI:10.3969/j.issn.1674-8034.2014.04.004.


[Abstract] Objective: To investigate the clinical characteristics of magnetic resonance imaging (MRI) for the breast intraductal papilloma, and to help improve the diagnostic accuracy of the MRI for this lesion.Materials and Methods: Postoperative pathology was used as the gold standard, a total of 76 patients with breast intraductal papillom were collected, including 7 patients with bilateral breast neoplasms. Clinical characteristics of the preoperative MRI image data were analyzed, including morphological features of the lesion, the signal characteristics of the lesion for T2WI and diffusion weighted imaging (DWI), the internal reinforcement method, and the characteristics of hemodynamics.Results: The average largest diameter line of the lesions was 1.3 cm, range from 0.2 cm to 9.8 cm. Morphology of the lesions were summarized as follows: round 51 cases, elliptic 13 cases, irregularly shaped 11 cases, lobulated 8 cases. Seventy-three cases showed clear margin while the other 10 cases didn’t. For the fat suppressed signal on T2WI, the number of cases with mixed hyper-intensity, iso-intensity, and hyper-intensity was 40, 34 and 9, respectively. There were 3 patients with unilateral lesion didn’t get the DWI result, 59 cases showed hyper-intensity, and 21 cases showed iso-intensity on DWI. The average value of apparent diffusion coefficients (ADC) of the lesions was 1.15×10-3 mm2/s, ranges from 0.82×10-3 mm2/s to 1.42×10-3 mm2/s. Fifty cases showed homogeneous enhancement and the other 33 showed heterogeneous enhancement. For the type of time-signal intensity curve, numbers of platform, outflow and sustained ascending was 22, 33, and 28, respectively. There were 16 cases in association with duct dilatation, among which 11 cases were cystic and solid.Conclusions: The characteristics of the MRI for the breast intraductal papilloms generally present as round lesion with clear margin, mixed hyper- or iso-intensity on T2WI, and with homogeneous enhancement. All these characteristics are valuable for accurate diagnosis.
[Keywords] Breast neoplasms；Papilloma, intraductal；Magnetic resonance imaging；Diagnosis, differential

ZHANG Ren-zhi Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China

ZHOU Chun-wu* Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China

LI Jing Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China

OUYANG- Han Department of Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China

*Correspondence to: Zhou CW, E-mail: cjr.zhouchunwu@vip.163.com

Conflicts of interest   None.

Received  2014-04-03
Accepted  2014-05-08
DOI: 10.3969/j.issn.1674-8034.2014.04.004
DOI:10.3969/j.issn.1674-8034.2014.04.004.

[1]
徐开,唐迪.乳腺X线诊断.上海:上海科学技术出版社, 1980: 40-41.
[2]
Kurz KD, Roy S, Saleh A, et al. MRI features of intrauductal papilloma of the breast:sheep in wolf’s clothing? Acta Radiol, 2011, 52(3): 264-272.
[3]
阮玫,赵亚娥,汪登斌,等.乳腺导管内乳头状瘤的乳腺专用磁共振成像表现及其诊断价值.放射学实践, 2013, 28(3): 341-345.
[4]
Brookes MJ, Bourke AG. Radiological appearances of papillary breast lesions. Clin Radiol, 2008, 63(11): 1265-1273.
[5]
张静,蔡幼铨,程流泉,等.磁共振容易误诊的乳腺良性病例临床研究.武警医学, 2009, 20(5): 428-431.
[6]
Bhattarai N, Kanemaki Y, Kurihara Y, et al. Intraductal papilloma: features on MR ductography using a microscopic coil. Am J Roentgenol, 2006, 186(1): 44-47.
[7]
Daniet BL, Gardner RW, Birdwell RL, et al. Magnetic resonance imaging of intraductalpapilloma of the breast. Magn Reson Imaging, 2003, 21(3): 887-892.
[8]
Tominaga J, Hama H, Kimura N, et al. Magnetic resonance imaging of intraductal papillomas of the breast. J Comput Assist Tomogr, 2011, 35(1): 153-157.
[9]
Eiada R, Chong J, Kulkarni S, et al. Papillary lesions of the breast: MRI, ultrasound, and mammographic appearances. AJR Am J Roentgenol, 2012, 198(2): 264-271.
[10]
Richter-Ehrenstein C, Tombokan F, Fallenberg E, et al. Intraductal papillomas of the breast: diagnosis and management of 151 patients. Breast, 2011, 20(6): 501-504.
[11]
张仁知,周纯武,李静,等. MR扩散加权成像诊断非特殊型浸润性导管癌的价值.中华放射学杂志, 2012, 46(12): 1071-1074.
[12]
American College of Radiology. Breast imaging reporting and data system atlas (BI-RADS atlas). Reston: American College of Radiology, 2003(2): 98
[13]
Rizzo M, Linebarger J, Lowe MC, et al. Management of papillary breast lesions diagnosed on core-needle biopsy: clinical pathologic and radiologic analysis of 276 cases with surgical follow-up. J Am Coll Surg, 2012, 214(3): 280-287.

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