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• Clinical Article •
The apparent diffusion coefficient measurement in diagnosis of axillary lymph node lesions with multi b values and optimizing b value
CHEN Quan-hua  LIU Biao 

DOI:10.3969/j.issn.1674-8034.2014.04.005.


[Abstract] Objective: To compare apparent diffusion coefficient measurement of benign axillary lymph node and malignant axillary lymph node identification value and optimizing b value.Materials and Methods: By collecting in the hospital for breast dynamic contrast-enhanced scans and diffusion-weighted imaging,using three b values (400, 800, 1000 s/mm2). 59 patients (96 lymph nodes) with a clear outcome of the surgery and pathology and/or needle biopsy results were retrospectively analyzed.Results: The ADC values of malignant lesions were signifi cantly lower than those of benign lesions(P=0.00).The sensitivity and specificity were 88.53% and 62.85%, 77.14% and 78.69%, 77.14% and 81.97% respectively when b=400, 800 and 1000 by using a threshold ADC of less than 1.240, 0.955, 0.890×10-3mm2/s respectively. Areas under the curve are 0.828, 0.849, 0.873 as b=400 s/mm2, 800 s/mm2, 1000 s/mm2, respectively.Conclusions: The ADC value has moderate diagnosis potency in differentiating benign and malignant lymph node. The optimal b value is 1000 s/mm2.
[Keywords] Breast neoplasms；Axillary lymph node；Diffusion magnetic resonance imaging

CHEN Quan-hua Deparment of Radiology, the Eighth Affiliated Hospital of Guangxi Medical University, Guigang 537100, China

LIU Biao* Deparment of Radiology, the Eighth Affiliated Hospital of Guangxi Medical University, Guigang 537100, China

*Correspondence to: Liu B, E-mail: gyfsk@163.com

Conflicts of interest   None.

Received  2014-03-26
Accepted  2014-05-08
DOI: 10.3969/j.issn.1674-8034.2014.04.005
DOI:10.3969/j.issn.1674-8034.2014.04.005.

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