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• Clinical Article •
Correlation on MRI non-morphological features and C-erbB-2 expression of breast cancer
WEI Wei  XIE Dong  SU Dan-ke  ZHANG Wei  ZHAO Xin  LUO Ning-bin 

DOI:10.3969/j.issn.1674-8034.2014.04.006.


[Abstract] Objective: To explore the correlations of MRI non-morphological features (hemodynamic performance and function characteristics) and C-erbB-2 of breast cancer.Materials and Methods: Seventy-seven patients diagnosed as breast cancers by pathologic examination were reviewed, analysis the MRI non-morphological features and the C-erbB-2 expression, to explore pathological changes of time-signal intensity curve, early intensive rate and ADC values, using t-test and chi-square test and Spearman rank correlation analysis with the correlation of C-erbB-2 expression.Results: The time-signal intensity curve of breast cancer, early intensive rate had no correlation with C-erbB-2 expression, ADC values had negative correlation with C-erbB-2 expression, ADC values differences between the groups of C-erbB-2 expression was statistically significant, the best threshold of ADC value to judgment C-erbB-2 expression was 0.988×10-3mm2/s by ROC curve.Conclusions: C-erbB-2 expression had no correlation with MRI hemodynamic performance indicators, had negative correlation with ADC values.
[Keywords] Breast neoplasms；Magnetic resonance imaging

WEI Wei Department of Radiology, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China

XIE Dong Department of Radiology, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China

SU Dan-ke Department of Radiology, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China

ZHANG Wei Department of Radiology, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China

ZHAO Xin Department of Radiology, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China

LUO Ning-bin Department of Radiology, the Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China

Conflicts of interest   None.

Received  2014-03-19
Accepted  2014-05-10
DOI: 10.3969/j.issn.1674-8034.2014.04.006
DOI:10.3969/j.issn.1674-8034.2014.04.006.

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