Share：
Share this content in WeChat
X
[Chinese][PDF]112565
• Clinical Article •
Value of magnetic resonance imaging in parametrial invasion of cervical cancer
ZHANG Jie  XUE Hua-dan  LI Shuo  ZHANG Hai-bo  ZHOU Hai-long  HOU Bo  SUN Zhao-yong  JIN Zheng-yu 

DOI:10.3969/j.issn.1674-8034.2014.04.010.


[Abstract] Objective: To investigate the value of magnetic resonance imaging (MRI) in parametrial invasion of cervical cancer.Materials and Methods: Fifty-eight consecutive patients with histopathologically confirmed cervical cancer were collected. MRI findings were compared with the pathologic findings in all cases. The parametrial invasion was evaluated in the following four groups, T2 weighted imaging (T2WI), T2WI combined with diffusion-weighted imaging (DWI), T2WI combined with contrast enhancement and T2WI combined with DWI and contrast enhancement.Results: Among these 58 patients, 8 patients had parametrial invasion. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of T2WI were 87.5%, 90.0%, 58.3%, 97.8%, 89.7%. Those of T2WI combined with DWI were 87.5%, 96.0%, 77.8%, 98.0%, 94.8%. Those of T2WI combined with contrast enhancement were 62.5%, 100.0%, 100.0%, 94.3%, 94.8%. Those of T2WI combined with DWI and contrast enhancement were 87.5%, 100.0%, 100.0%, 98.0%, 98.3%.Conclusions: T2WI combined with DWI and contrast enhancement is superior to other three groups in the evaluation of parametrial invasion.
[Keywords] Cervix neoplasms；Neoplasm invasiveness；Magnetic resonance imaging

ZHANG Jie Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

XUE Hua-dan Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

LI Shuo Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

ZHANG Hai-bo Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

ZHOU Hai-long Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

HOU Bo Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

SUN Zhao-yong Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

JIN Zheng-yu* Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

*Correspondence to: Jin ZY, E-mail: jin_zhengyu@163.com

Conflicts of interest   None.

Received  2013-12-21
Accepted  2014-04-25
DOI: 10.3969/j.issn.1674-8034.2014.04.010
DOI:10.3969/j.issn.1674-8034.2014.04.010.

[1]
Kodama J, Kusumoto T, Nakamura K, et al. Factors associated with parametrial involvement in stage IB1 cervical cancer and identification of patients suitable for less radical surgery. Gynecol Oncol, 2011, 122(3): 491-494.
[2]
Van de Putte G, Lie AK, Vach W, et al. Risk grouping in stage IB squamous cell cervical carcinoma. Gynecol Oncol, 2005, 99(1): 106-112.
[3]
Choi HJ, Ju W, Myung SK, et al. Diagnostic performance of computer tomography, magnetic resonance imaging, and positron emission tomography or positron emission tomography/computer tomography for detection of metastatic lymph nodes in patients with cervical cancer: Meta-analysis. Cancer Sci, 2010, 101(6): 1471-1479.
[4]
Chung HH, Kang SB, Cho JY, et al. Can preoperative MRI accurately evaluate nodal and parametrial invasion in early stage cervical cancer? Jpn J Clin Oncol, 2007, 37(5): 370-375.
[5]
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2007. CA Cancer J Clin, 2007, 57(1): 43-66.
[6]
Kato T, Watari H, Takeda M, et al. Multivariate prognostic analysis of adenocarcinoma of the uterine cervix treated with radical hysterectomy and systematic lymphadenectomy. J Gynecol Oncol, 2013, 24(3): 222-228.
[7]
Jung DC, Kim MK, Kang S, et al. Identification of a patient group at low risk for parametrial invasion in early-stage cervical cancer. Gynecol Oncol, 2010, 119(3): 426-430.
[8]
Rob L, Charvat M, Robova H, et al. Less radical fertility-sparing surgery than radical trachelectomy in early cervical cancer. Int J Gynecol Cancer, 2007, 17(1): 304-310.
[9]
Shin SJ, Kim KR, Song DE, et al. Recognition of parametrial invasion, an important landmark when treating cervical cancer. Gynecol Oncol, 2012, 124(3): 502-507.
[10]
Sala E, Wakely S, Senior E, et al. MRI of malignant neoplasms of the uterine corpus and cervix. AJR Am J Roentgenol, 2007, 188(6): 1577-1587.
[11]
Giuliano R, Cristina V, Andrea S, et al. Diagnostic accuracy of MRI in primary cervical cancer. Open J Radiology, 2012, 2(1): 14-21.
[12]
Chen YB, Hu CM, Chen GL, et al. Staging of uterine cervical carcinoma: whole-body diffusion-weighted magnetic resonance imaging. Abdom Imaging, 2011, 36(5): 619-626.
[13]
Hoogendam JP, Klerkx WM, de Kort GA, et al. The influence of the b-value combination on apparent diffusion coefficient based differentiation between malignant and benign tissue in cervical cancer. J Magn Reson Imaging, 2010, 32(2): 376-382.
[14]
Charles-Edwards EM, Messiou C, Morgan VA, et al. Diffusion-weighted imaging in cervical cancer with an endovaginal technique: potential value for improving tumor detection in stage Ia and Ib1 disease. Radiology, 2008, 249(2): 541-550.
[15]
Akita A, Shinmoto H, Hayashi S, et al. Comparison of T2-weighted and contrast-enhanced T1-weighted MR imaging at 1.5 T for assessing the local extent of cervical carcinoma. Eur Radiol, 2011, 21(9): 1850-1857.
[16]
Tsuda K, Murakami T, Kurachi H, et al. MR imaging of cervical carcinoma: comparison among T2-weighted, dynamic, and postcontrast T1-weighted images with histopathological correlation. Abdom Imaging, 1997, 22(1): 103-107.
[17]
Seki H, Azumi R, Kimura M, et al. Stromal invasion by carcinoma of the cervix: assessment with dynamic MR imaging. AJR Am J Roentgenol, 1997, 168(6): 1579-1585.
[18]
Nicolet V, Carignan L, Bourdon F, et al. MR imaging of cervical carcinoma: a practical staging approach. Radiographics, 2000, 20(6): 1539-1549.
[19]
Iwata S, Joja I, Okuno K, et al. Cervical carcinoma with full-thickness stromal invasion: efficacy of dynamic MR imaging in the assessment of parametrial involvement. Radiat Med, 2002, 20(5): 247-255.
[20]
Haider MA, Sitartchouk I, Roberts TP, et al. Correlations between dynamic contrast-enhanced magnetic resonance imaging-derived measures of tumour microvasculature and interstitial fluid pressure in patients with cervical cancer. J Magn Reson Imaging, 2007, 25(1): 153-159.

PREV MRI features of xanthogranulomatous cholecystitis
NEXT The differential diagnosis between benign and malignant bone tumors
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn