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• Clinical Article •
Value of magnetic resonance imaging in parametrial invasion of cervical cancer
ZHANG Jie  XUE Hua-dan  LI Shuo  ZHANG Hai-bo  ZHOU Hai-long  HOU Bo  SUN Zhao-yong  JIN Zheng-yu 

DOI:10.3969/j.issn.1674-8034.2014.04.010.


[Abstract] Objective: To investigate the value of magnetic resonance imaging (MRI) in parametrial invasion of cervical cancer.Materials and Methods: Fifty-eight consecutive patients with histopathologically confirmed cervical cancer were collected. MRI findings were compared with the pathologic findings in all cases. The parametrial invasion was evaluated in the following four groups, T2 weighted imaging (T2WI), T2WI combined with diffusion-weighted imaging (DWI), T2WI combined with contrast enhancement and T2WI combined with DWI and contrast enhancement.Results: Among these 58 patients, 8 patients had parametrial invasion. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of T2WI were 87.5%, 90.0%, 58.3%, 97.8%, 89.7%. Those of T2WI combined with DWI were 87.5%, 96.0%, 77.8%, 98.0%, 94.8%. Those of T2WI combined with contrast enhancement were 62.5%, 100.0%, 100.0%, 94.3%, 94.8%. Those of T2WI combined with DWI and contrast enhancement were 87.5%, 100.0%, 100.0%, 98.0%, 98.3%.Conclusions: T2WI combined with DWI and contrast enhancement is superior to other three groups in the evaluation of parametrial invasion.
[Keywords] Cervix neoplasms；Neoplasm invasiveness；Magnetic resonance imaging

ZHANG Jie Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

XUE Hua-dan Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

LI Shuo Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

ZHANG Hai-bo Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

ZHOU Hai-long Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

HOU Bo Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

SUN Zhao-yong Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

JIN Zheng-yu* Department of Radiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

*Correspondence to: Jin ZY, E-mail: jin_zhengyu@163.com

Conflicts of interest   None.

Received  2013-12-21
Accepted  2014-04-25
DOI: 10.3969/j.issn.1674-8034.2014.04.010
DOI:10.3969/j.issn.1674-8034.2014.04.010.

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