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Research progress in bio-responsive MRI contrast agent
ZENG Qi  WANG Tian-yu  TANG Jian-bin 

DOI:10.3969/j.issn.1674-8034.2014.05.014.


[Abstract] Different tissues and diseases have specific biological signals. The development of magnetic resonance imaging (MRI) contrast agents responding to these signals can not only improve the sensitivity of disease detection by MRI, but also increase the accuracy of disease diagnosis through molecular imaging of these disease signals. This paper gives a review of MRI contrast agents responding to albumin, pH, metal ion, enzyme, redox and other biological signals with the focus on the latest developments and perspectives.
[Keywords] Magnetic resonance imaging；Contrast media

ZENG Qi Department of Chemical and Biological Engineering, Center for Bioengineering, Zhejiang University, Hangzhou 310027, China

WANG Tian-yu Department of Chemical and Biological Engineering, Center for Bioengineering, Zhejiang University, Hangzhou 310027, China

TANG Jian-bin* Department of Chemical and Biological Engineering, Center for Bioengineering, Zhejiang University, Hangzhou 310027, China

*Correspondence to: Tang JB, E-mail: jianbin@zju.edu.cn

Conflicts of interest   None.

Received  2014-05-13
Accepted  2014-06-08
DOI: 10.3969/j.issn.1674-8034.2014.05.014
DOI:10.3969/j.issn.1674-8034.2014.05.014.

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