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• Editorial •
Clinical application and advances of functional magnetic resonance imaging
GONG Qi-yong  LV Su 

DOI:10.3969/j.issn.1674-8034.2014.05.S1.014.


[Abstract] In recent decades, the rapid development of multi-modal functional magnetic resonance imaging has brought great influence in clinical medicine, also provided an important means for psychiatry disorder research. This paper reviewed functional magnetic resonance imaging methods and image post-processing techniques, as well as its application in reflecting functional changes in subclinical disease, real-time locating of brain function area in vivo and exploring the mechanism of treatment. The technical shortcomings and future directions are also clarified.
[Keywords] Functional magnetic resonance imaging；Clinical application；Brain function；Psychiatry disorder

GONG Qi-yong * Huaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, China

LV Su Huaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan University, Chengdu 610041, China

*Correspondence to: Gong QY, E-mail: qiyonggong@hmrrc.org.cn

Conflicts of interest   None.

致谢： 本文的撰写得到华西磁共振中心李飞博士和姚骊硕士的大力协助，特此致谢！
Received  2014-08-26
Accepted  2014-09-25
DOI: 10.3969/j.issn.1674-8034.2014.05.S1.014
DOI:10.3969/j.issn.1674-8034.2014.05.S1.014.

[1]
Bullmore E, Sporns O. Complex brain networks: graph theoretical analysis of structural and functional systems. Nat Rev Neurosci, 2009, 10(3):186-198.
[2]
Sporns O, Tononi G, Kötter R. The human connectome: A structural description of the human brain. PLoS Comput Biol, 2005, 1(4):e42.
[3]
Sporns O. Small-world connectivity, motif composition, and complexity of fractal neuronal connections. Biosystems, 2006, 85(1): 55-64.
[4]
Bullmore E, Sporns O. The economy of brain network organization. Nat Rev Neurosci, 2012, 13(5):336-349.
[5]
van den Heuvel MP, Sporns O, Collin G, et al. Abnormal rich club organization and functional brain dynamics in schizophrenia. JAMAPsychiatry, 2013, 70(8):783-792.
[6]
McGuire P, Howes OD, Stone J, et al. Functional neuroimaging in schizophrenia: diagnosis and drug discovery. Trends in Pharmacological Sciences, 2008. 29(2): 91-98.
[7]
张体江，龚启勇．磁化传递成像及其在精神疾病中的研究现状．磁共振成像, 2010, 1(6):468-472.
[8]
Lui S, Huang X, Chen L, et al. High-field MRI reveals an acute impact on brain function in survivors of the magnitude 8.0 earthquake in China. Proc Natl Acad Sci U S A, 2009, 106(36):15412-15417.
[9]
Wang L, Brier MR, Snyder AZ, et al. Cerebrospinal fluid Abeta42, phosphorylated Tau181, and resting-state functional connectivity. JAMA Neurol, 2013, 70(10):1242-1248.
[10]
Orrù G1, Pettersson-Yeo W, Marquand AF, et al. Using Support Vector Machine to identify imaging biomarkers of neurological and psychiatric disease: a critical review. Neurosci Biobehav Rev, 2012, 36(4):1140-1152.
[11]
Zeng LL, Shen H, Liu L, et al. Identifying major depression using whole-brain functional connectivity: a multivariate pattern analysis. Brain, 2012, 135(Pt 5):1498-507.
[12]
Pettersson-Yeo W, Benetti S, Marquand AF, et al. Using genetic, cognitive and multi-modal neuroimaging data to identify ultra-high-risk and first-episode psychosis at the individual level. Psychol Med, 2013, 43(12):2547-2562.
[13]
Gong Q, Li L, Du M, et al. Quantitative prediction of individual psychopathology in trauma survivors using resting-state FMRI. Neuropsychopharmacology, 2014, 39(3): 681-687.
[14]
Newman MEJ. The structure and function of complex networks. SIAM Review, 2003, 45:167-256.
[15]
Meng LL, Sun XJ. Advances of magnetic resonance perfusion imaging in hypertensive cerebrovascular diseases. Chin J Magn Reson Imaging, 2011, 2(5):384-387.
[16]
延根，赵大威，戴卓智，等．评估量化超急性期缺血性脑卒中发病时间窗的研究.磁共振成像, 2014. 5(1):60-65.
[17]
Röder CH, Dieleman S, van der Veen FM, et al. Systematic review of the influence of antipsychotics on the blood oxygenation level-dependent signal of functional magnetic resonance imaging. Curr Med Chem, 2013, 20(3):448-461.
[18]
Abbott CC, Jaramillo A, Wilcox CE, et al. Antipsychotic drug effects in schizophrenia: a review of longitudinal FMRI investigations and neural interpretations. Curr Med Chem, 2013, 20(3):428-437.
[19]
Lui S, Li T, Deng W, et al. Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by "resting state" functional magnetic resonance imaging. Arch Gen Psychiatry, 2010, 67(8):783-792.
[20]
Moncrieff J, Leo J. A systematic review of the effects of antipsychotic drugs on brain volume. Psychol Med, 2010, 40(9):1409-1422.
[21]
Hafeman DM, Chang KD, Garrett AS, et al. Effects of medication on neuroimaging findings in bipolar disorder: an updated review. Bipolar Disord, 2012, 14(4):375-410.
[22]
Hampel H, Prvulovic D, Teipel SJ, et al. Recent developments of functional magnetic resonance imaging research for drug development in Alzheimer’s disease. Progress in Neurobiology, 2011, 95(4):570-578.
[23]
Bennett CM, Miller MB. Miller, How reliable are the results from functional magnetic resonance imaging? Ann N Y Acad Sci, 2010, 1191:133-155.
[24]
薛正和，王永峰，赵一冰．磁共振成像的质量控制及参数优化．磁共振成像, 2013, 4(6):441-444.
[25]
Keller CJ, Bickel S, Entz L, et al. Intrinsic functional architecture predicts electrically evoked responses in the human brain. Proc Natl Acad Sci USA, 2011, 108(25):10308-10313.
[26]
Entz L, Tóth E, Keller CJ, et al. Evoked effective connectivity of the human neocortex. Hum Brain Mapp, 2014. DOI: 10.1002/hbm.22581. [ DOI: ]

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