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• Clinical Article •
The study of difference of white matter degeneration between urban and rural population in Beijing
JIANG Wen  JING Jing  LIANG Wei  LV Yan-wei  CHENG Xiao-guang 

DOI:10.3969/j.issn.1674-8034.2014.06.008.


[Abstract] Objective: To evaluate the difference of degree of white matter degeneration between urban and rural population in Beijing.Material and Methods: Except cerebral infarction (diagnosed by DWI), hemorrhage, hydrocephalus and other white matter degeneration diseases, the MR image was obtained in a cohort of 41 urban [aged 56—72 years, mean age (62.85±4.28) years, 13 males and 28 females] and 41 rural patients [aged 56-69 years, mean age (62.68±4.00) years, 17 males and 24 females] who live in Beijing. The Fazekas scale was used to evaluate the degree of white matter degeneration. Independent-samples t test was made to exclude effect of age, and χ2 test was made to exclude the effect of gender. Independent-samples rank sum test was made to evaluate the difference of degree of white matter degeneration between urban and rural population. Rank correlation was made to evaluate the influence of age on total score according to the Fazekas scale.Results: There was statistically significant difference in degree of white matter degeneration between urban and rural population in Beijing (Z=-2.730, P=0.006, P<0.05). And the influence of age (t=0.187, P=0.852, P>0.05) and gender (P=0.395, P>0.05) can be excluded. The degree of white matter degeneration in rural population (mean rank 48.15) was more serious than that in urban population (mean rank 34.85). There was correlation between age and total score (r=0.484, P=0.000, P<0.05). The degree of white matter degeneration increased with age.Conclusions: The degree of white matter degeneration in rural population in Beijing is more severe than that in urban population. Rural population in Beijing may have a greater possibility of cerebral vascular disease and cognitive disorder. Therefore, more attention should be paid to rural population.
[Keywords] Leukoencephalopathy, progressive multifocal；Magnetic resonance imaging；Fazekas scale

JIANG Wen Department of Radiology of Beijing Jishuitan Hospital, Beijing 100035, China

JING Jing Department of Neurology of Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

LIANG Wei Department of Radiology of Beijing Jishuitan Hospital, Beijing 100035, China

LV Yan-wei Department of Statistics of Beijing Jishuitan Hospital, Beijing 100035, China

CHENG Xiao-guang * Department of Radiology of Beijing Jishuitan Hospital, Beijing 100035, China

*Correspondence to: Cheng XG, E-mail: Xiao65@263.net

Conflicts of interest   None.

Received  2014-07-10
Accepted  2014-10-10
DOI: 10.3969/j.issn.1674-8034.2014.06.008
DOI:10.3969/j.issn.1674-8034.2014.06.008.

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