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• Clinical Article •
The application of conventional MRI, DWI and DCEI in focal liver lesions
ZHOU Ting-ting  WANG Jian-liang  YANG Yi  ZHAO Wen-lu  SHEN Jun-kang 

DOI:10.3969/j.issn.1674-8034.2015.01.007.


[Abstract] Objective: The purpose of this study was to compare the diagnostic performances of conventional respiratory triggered T2WI, DWI and dynamic contrast enhanced imaging sequences in the evaluation of focal liver lesions (FLLs).Materials and Methods: We collected liver MRI data of twenty-three patients from 2011.9 to 2013.1. Two observers reviewed T2WI, DWI and DCEI for FLLs detection and characterization, then compared T2WI, DWI, DCEI and DCEI combined with DWI for FLLs detection. The reviewers then characterized each detected lesion using a 5-point scale, the sensitivity, specificity and areas under the receiver operating characteristic curve (Az) for the detection of liver lesions were evaluated using receiver operating characteristic analysis.Results: Overall detection rate was equal for T2WI, DWI and DCEI, but ≤5 mm lesions detection rate was lower for DWI (44.44%) versus T2-weighted imaging (66.67%) (P=0.004). Overall detection rate of DCEI combined with DWI (100%) was significantly higher than T2WI (87.14%), DWI (88.57%) and DCEI (87.14%) alone (P≤0.006). Benign and ≤5 mm lesions detection rate are higher for DCEI combined with DWI (100%、100%)versus DWI (87.23%、44.44%) (P≤0.029). There was no significant difference between the three image sets (T2WI, DWI, DCEI) in the detection of FLLs with regards to Az (≥0.075). However, the Az values of DCEI combined with DWI (0.982) was significantly higher than those of DWI (0.886) and T2WI (0.858) (P≤0.0199).Conclusions: The diagnostic performance of DCEI and DWI is equal to conventional respiratory triggered T2WI. Combination of DCEI and DWI increases the lesions detection and diagnostic performance.
[Keywords] Liver neoplasms；Magnetic resonance imaging

ZHOU Ting-ting Department of Radiology, the First People’s Hospital of Kunshan, Suzhou 215300, China

WANG Jian-liang* Department of Radiology, the First People’s Hospital of Kunshan, Suzhou 215300, China

YANG Yi Department of Image, the Second Hospital Affiliated to Suzhou University, Suzhou 215004, China

ZHAO Wen-lu Department of Image, the Second Hospital Affiliated to Suzhou University, Suzhou 215004, China

SHEN Jun-kang Department of Image, the Second Hospital Affiliated to Suzhou University, Suzhou 215004, China

*Correspondence to: Wang JL, Email: wjlks@sina.com

Conflicts of interest   None.

Received  2014-08-07
Accepted  2014-09-30
DOI: 10.3969/j.issn.1674-8034.2015.01.007
DOI:10.3969/j.issn.1674-8034.2015.01.007.

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