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• Clinical Article •
Image features and pathological manifestations of inflammatory myofibroblastic tumor of abdominal-pevic and review of literature
XU Fan  WU Mei  GUO Yuan  GUO Yong-mei  WU Hong-zhen  ZHANG Bo 

DOI:10.3969/j.issn.1674-8034.2015.01.008.


[Abstract] Objective: To conclude CT and MR image features of the inflammatory myofibroblastic tumor of Abdominal-Pevic, and compare with pathology, in order to improve the preoperative diagnostic accuracy of the disease.Materials and Methods: Eight cases with IMT of Abdominal-Pevic confirmed by surgery pathology were retrospectively analyzed including 5 males and 3 females, age from 38 to 78 years, mean age 54 years. Clinical manifestation was abdominal pain, or liver area pain (3 cases), no obvious cause angular in 2 cases, 3 cases were found by medical examination. Among 8 cases, 7 underwent CT scanning, while the 3 cases underwent both CT and MRI examination. To review the imaging signs and compare with pathology.Results: Each 1 case located in bladder, mesenterium, and kidney, 5 cases located in liver. 5 cases had ill-defined margin. Plain CT showed the uneven density with the 8 cases, in MR, the tumor showed iso-hypointensity on T1WI and slightly iso-hyperintensity on T2WI. They showed variable patterns of contrast enhancement: 4 cases showed ring-shaped enhancement, 3 cases showed mild edge enhancement, 3 case showed gradual enhancement. Microscopically, the tumor were mainly composed of spindle shaped fibrous cells and inflammatory cells (mainly plasma cells and lymphocyte). Cells had no manifest heteromorphism. Immunohistochemically, Vimentin (6/6) and SMA (7/7) were positive in all the cases, ALK (1/8) and CD-68 (2/8) were partly positive expression, other markers such as S-100, CD117, CD34 were negative expression.Conclusions: CT and MR had the value for the localization and qualitation diagnosis and differential diagnosis of IMT, careful analysis of the enhancement is expected to propose propensity diagnosis. But the definite diagnose relies on pathological and immunohistochemical study.
[Keywords] Pelvic neoplasms；Tomography；X-ray computed；Magnetic resonance imaging

XU Fan Department of Radiology, the Affiliated Guangzhou First People's Hospital, Guangzhou medical University, Guangzhou 510180, China

WU Mei* Department of Radiology, the Affiliated Guangzhou First People's Hospital, Guangzhou medical University, Guangzhou 510180, China

GUO Yuan Department of Radiology, the Affiliated Guangzhou First People's Hospital, Guangzhou medical University, Guangzhou 510180, China

GUO Yong-mei Department of Radiology, the Affiliated Guangzhou First People's Hospital, Guangzhou medical University, Guangzhou 510180, China

WU Hong-zhen Department of Radiology, the Affiliated Guangzhou First People's Hospital, Guangzhou medical University, Guangzhou 510180, China

ZHANG Bo Department of Radiology, the Affiliated Guangzhou First People's Hospital, Guangzhou medical University, Guangzhou 510180, China

*Correspondence to: Wu M, E-mail: may9@sina.com

Conflicts of interest   None.

Received  2014-08-21
Accepted  2014-10-10
DOI: 10.3969/j.issn.1674-8034.2015.01.008
DOI:10.3969/j.issn.1674-8034.2015.01.008.

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