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Clinical Article
Comparing cardiac magnetic resonance with echocardiogram on diagnosis of apical hypertrophic cardiomyopathy
YUAN Si-shu  LI Zhi-wei  XIA Li-ming 

DOI:10.3969/j.issn.1674-8034.2015.03.006.


[Abstract] Objective: To discuss the character of cardiac magnetic resonance and echocardiogram findings of apical hypertrophic cardiomyopathy (AHCM), and evaluate the diagnostic value of CMR and echocardiogram in AHCM.Materials and Methods: Twenty-one patients (male 16, female 5) with AHCM underwent Cardiac Magnetic Resonance, echocardiogram, ECG and coronary angiography.Results: The cardiac magnetic resonance revealed apical hypertrophic in all the patients. Among them, 13 patients were pure form P-AHCM, 1 patient was pure form T-AHCM, 1 patient was mixed form P-AHCM, and 6 patients were mixed form T-AHCM. Magnetic resonance imaging showed "ace of spades" morphology of the left ventricle in all the T-AHCM patients. Four patients underwent myocardial contrast enhancement MR scanning: 3 patients presented LGE, 2 patients presented myocardial ischemia, and 2 patients presented myocardial infarction. Echocardiography provided correct diagnoses in 6/21 patients (28.6%), while in 10 patients echocardiographic results were normal. All of our patients showed electrocardiographic alterations of the ventricular repolarization: 14 patients (67.7%) with LV high voltage. Seventeen patients (80.9%) with giant negative T waves. Sixteen patients (76.2%) with a significant descending ST segment. Four patients had arrhythmia in different degrees.Conclusions: MR has higher sensitivity in diagnosing AHCM than echocardiogram. The ECG is a helpful tool to screen AHCM. To the patients who is suspected of AHCM, cardiac magnetic resonance could make a definite diagnosis.
[Keywords] Magnetic resonance imaging;Echocardiogram;Apical hypertrophic;Cardiomyopathy

YUAN Si-shu Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China

LI Zhi-wei Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China

XIA Li-ming* Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China

*Correspondence to: Xia LM, E-mail: cjr.xialiming@vip.163.com

Conflicts of interest   None.

Received  2014-10-07
Accepted  2014-12-01
DOI: 10.3969/j.issn.1674-8034.2015.03.006
DOI:10.3969/j.issn.1674-8034.2015.03.006.

[1]
王树贤,丁康,徐艳燕,等.超声心动图对早期心尖肥厚型心肌病的诊断价值.中国循环杂志, 2005, 20(3): 215-216.
[2]
尹刚,贺光军,赵世华.心血管MRI第二部分:心血管MRI的基本序列和常用技术.磁共振成像, 2013, 4(5): 382-388.
[3]
韦云青,赵世华,陆敏杰,等.心尖肥厚型心肌病的MRI诊断.中华放射学杂志, 2007, 41(8): 800-804.
[4]
Sakamoto T, Tei C, Murayama M, et al. Giant T wave inversion as a manifestation of asymmetrical apical hypertrophy (AAH) of the left ventricle: echocardiographic and ultrasono-cardiotomographic study. Jpn Heart J, 1976, 41(17): 611-629.
[5]
Yan LR, Wang ZM, Xu ZM, et al. Two hundred eight patients with apical hypertrophic cardiomyopathy in China: clinical feature, prognosis, and comparison of pure and mixed forms. Clin Cardiol, 2012, 35(2): 101-106.
[6]
Koga Y, Itaya K, Toshima H. Prognosis in hypertrophic cardiomyopathy. Am Heart J, 1984, 108(2): 351-359.
[7]
Kitaoka H, Doi Y, Casey SA, et al. Comparison of prevalence of apical hypertrophic cardiomyopathy in Japan and the United States. Am J Cardiol, 2003, 92(10): 1183-1186.
[8]
Maron BJ. Hypertrophic cardiomyopathy: a systematic review. JAMA, 2002, 287(10): 1308-1320.
[9]
Eriksson MJ, Sonnenberg B, Woo A, et al. Long-term outcome in patients with apical hypertrophic cardiomyopathy. J Am Coll Cardiol, 2002, 39(4): 638-645.
[10]
张兆琪,徐磊.心脏MRI的应用现状与新技术进展.磁共振成像, 2013, 4(3): 218-225.
[11]
赵世华.心脏CT和MR如何选择.放射学实践, 2014, 29(7): 763-765.
[12]
Suzuki J, Shimamoto R, Nishikawa J, et a1. Morphological onset and early diagnosis in apical hypertrophic cardiomyopathy: a long term analysis with nuclear magnetic resonance imaging. J Am Coll Cardiol, 1999, 33(1): 146-151.
[13]
Adabag AS, Maron BJ, Appelbaum E, et al. Occurrence and frequency of arrhythmias in hypertrophic cardiomyopathy in relation to delayed enhancement on cardiovascular magnetic resonance. J Am Coll Cardiol, 2008, 51(14): 1369-1374.
[14]
Moon JC, McKenna WJ, McCrohon JA, et al. Toward clinical risk assessment in hypertrophic cardiomyopathy with gadolinium cardiovascular magnetic resonance. J Am Coll Cardiol, 2003, 41(9): 1561-1567.
[15]
Fattori R, Biagini E, Lorenzini M, et al. Significance of magnetic resonance imaging in apical hypertrophic cardiomyopathy. Am J Cardiol, 2010, 105(11): 1592-1596.
[16]
Bax JJ, Lamb H, Dibbets P, et al. Comparison of gated single-photon emission computed tomography with magnetic resonance imaging for evaluation of left ventricular function in ischemic cardiomyopathy. Am J Cardiol, 2000, 86(12): 1299-1305
[17]
Langerak SE, Vliegen HW, de Roos A, et al. Detection of vein graft disease using high-resolution magnetic resonance angiography. Circulation, 2002, 105(3): 328-333.
[18]
Sato Y, Matsumoto N, Kunisama T, et al. Myocardial fibrosis in a patient with apical hypertrophic cardiomyopathy detected by delayed-enhanced magnetic resonance imaging. Int J Cardiol, 2008, 131(1): 41-43.
[19]
李志伟,袁思殊,黄璐,等.心肌磁共振多b值DWI的初步探讨.磁共振成像, 2013, 28 (3): 337-340.

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