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• Clinical Article •
Diagnostic value of whole body diffusion weighted imaging in malignant lymphadenopathy
LI Li  SUO Ling-yun  Li Jing  REN Hui-peng  WANG Xiao-hu  REN Zhuan-qin 

DOI:10.3969/j.issn.1674-8034.2015.01.011.


[Abstract] Objective: To study the value and significance of the body diffusion-weighted imaging in the diagnosis and differential diagnosis between lymphoma and lymph node metastases.Material and Methods: Select 25 cases of clinically diagnosed lymphoma patients, 20 patients with lymph node metastases, and 15 healthy volunteers as control group, all lines of WB-DWI imaging and T2 fat suppression shaft can scan, record ADC values of all abnormal lymph nodes and the lymph nodes in the normal control group, the lymphoma group and the normal group, lymph node metastasis group and the normal group, lymphoma group and metastasis between groups ADC value two two comparison, to investigate whether the ADC value has significant differences in the diagnosis and differential diagnosis of malignant lymph node lesions. Try to determine the best differential diagnosis OT between lymphoma and lymph node metastasis under the receiver-operating characteristic curve (ROC curve) analysis.Results: Lymphoma group ADC value was (0.70±0.13) mm2/1000 s, lymph node metastasis group ADC value was (0.94±0.14) mm2/1000 s, normal control group ADC value was (1.23±0.24) mm2/1000 s, with the independent sample t test, lymphoma group with lymph node metastasis between groups ADC value with statistical significance (t=-16.395, P<0.05), lymphoma group and normal control group ADC value with statistical significance (t=-14.876, P<0.05), lymph node metastasis group and normal control group with statistical significance (t=-7.851, P<0.05). By ROC curve we obtained that when the ADC value was 0.79, AZ value was 0.910, which corresponds to the sensitivity 90.3%, specificity 80.6%, this time accurate index was the highest and the diagnostic efficacy best.Conclusions: Whole body diffusion weighted imaging has a good application prospect in diagnosis of systemic malignant lymphadenopathy, through quantitative analysis of ADC value can provide the reference basis for the distinction between the two.
[Keywords] Diffusion magnetic resonance imaging；Lymphoma；Lymph node

LI Li Department of Radiology, Baoji Central Hospital, Shaanxi Province, Baoji 721008, China

SUO Ling-yun Department of Radiology, Baoji Central Hospital, Shaanxi Province, Baoji 721008, China

Li Jing Department of Radiology, Baoji Central Hospital, Shaanxi Province, Baoji 721008, China

REN Hui-peng Department of Radiology, Baoji Central Hospital, Shaanxi Province, Baoji 721008, China

WANG Xiao-hu Department of Radiology, Baoji Central Hospital, Shaanxi Province, Baoji 721008, China

REN Zhuan-qin* Department of Radiology, Baoji Central Hospital, Shaanxi Province, Baoji 721008, China

*Correspondence to: Ren ZQ, E-mail: Renzhuanqin@163.com

Conflicts of interest   None.

Received  2014-08-26
Accepted  2014-11-16
DOI: 10.3969/j.issn.1674-8034.2015.01.011
DOI:10.3969/j.issn.1674-8034.2015.01.011.

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