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• Review •
Application of SPIO and 19F probes in magnetic resonance imaging to track in vivo immune cells
YANG Hai-jie  FENG Pei  WANG Mian  FENG Zhi-wei 

DOI:10.3969/j.issn.1674-8034.2015.03.015.


[Abstract] The increasing confinement of in vivo imaging technologies, combined with the development of emerging cell therapies, has led a revolution in the field of immune cell tracking in vivo. With the rapid improvement of SPIO- and 19F-based probes, range of magnetic resonance imaging (MRI) application is broadened. For example, MRI technologies have been introduced to image-guided immune cell delivery, and he visualization of immune cell homing and implantation, inflammation, and cell physiology. MRI-based cell tracking technologies have been widely used to follow the fate of immune cells in vivo, or evaluate the effect of cell therapy in vivo. This review focuses on the application of SPIO and 19F probes in magnetic resonance imaging to track in vivo immune cells.
[Keywords] Immune cells；Magnetic resonance imaging；Contrast media

YANG Hai-jie Xinxiang Medical University, Henan Province, Xinxiang 453003, China

FENG Pei Xinxiang Medical University, Henan Province, Xinxiang 453003, China

WANG Mian Xinxiang Medical University, Henan Province, Xinxiang 453003, China

FENG Zhi-wei* Xinxiang Medical University, Henan Province, Xinxiang 453003, China

*Correspondence to: Feng ZW, E-mail: xxyxy_fzw@163.com

Conflicts of interest   None.

Received  2014-08-06
Accepted  2014-09-26
DOI: 10.3969/j.issn.1674-8034.2015.03.015
DOI:10.3969/j.issn.1674-8034.2015.03.015.

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