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• Clinical Article •
Clinical application of DTI in mild traumatic brain injury and its significance
LI Jin  ZUO Chao  LIU Yun-yang  XIA Shuang  LI Mu  MA Jing-jian 

DOI:10.3969/j.issn.1674-8034.2015.04.006.


[Abstract] Objective: The purpose of this study was to detect intracranial axonal damage after mild traumatic brain injury using diffusion tensor imaging (DTI), and assess the application of DTI in mild traumatic brain injury clinically.Materials and Methods: Thirty patients were prospectively enrolled from Tianjin First Center Hospital, who sustained a mild TBI, 30 normal volunteers were also recruited as control. All the participants underwent routine MRI, DTI scanning, and Rivermead Post Concussion Symptoms Questionnaire (RPQ) within the day of examination.Results: The RPQ scores of mTBI patients were higher than control (P<0.01). Whole brain analysis of DTI revealed the areas with higher FA values: right cerebellum, occipital lobe, declive, lingual gyrus, the triangular part of right inferior frontal gyrus, Precuneus. The areas with lower FA values were the optic radiation, cerebral peduncle, corpus callosum, the white matter under middle frontal gyrus, the white matter under precentral gyrus.Conclusion: We had shown that DTI can identify abnormalities in patients following mTBI. DTI were sensitive in finding intracranial latent lesion by mTBI. We believed such early identification could certainly be used to help diagnosis, and might play a key role in prognosis of mTBI.
[Keywords] Craniocerebral trauma；Magnetic resonance imaging；Diffusion tensor imaging；Axonal injury；Post-concussive syndrome

LI Jin Tianjin Medical University First Center Hospital Neurosurgery Department, Tianjin 300190, China

ZUO Chao Tianjin Medical University First Center Hospital Radiology Department, Tianjin 300190, China

LIU Yun-yang Tianjin Medical University First Center Hospital Neurosurgery Department, Tianjin 300190, China

XIA Shuang Tianjin Medical University First Center Hospital Radiology Department, Tianjin 300190, China

LI Mu Tianjin Medical University First Center Hospital Neurosurgery Department, Tianjin 300190, China

MA Jing-jian* Tianjin Medical University First Center Hospital Neurosurgery Department, Tianjin 300190, China

*Correspondence to: Ma JJ, E-mail: jingjian212672@sina.com

Conflicts of interest   None.

Received  2014-11-03
Accepted  2015-01-04
DOI: 10.3969/j.issn.1674-8034.2015.04.006
DOI:10.3969/j.issn.1674-8034.2015.04.006.

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