Share：
Share this content in WeChat
X
[Chinese][PDF]105372
• Clinical Article •
Evaluation of T2WI and readout-segmented echo-planar imaging in diagnosing early prostate cancers: a study based on PI-RADS system
MIN Xiang-de  WANG Liang  FENG Zhao-yan  LI Liang  CAI Jie  DENG Ming  LI Ba-sen  KE Zan  FENG Ding-yi 

DOI:10.3969/j.issn.1674-8034.2015.04.010.


[Abstract] Objectives: To compare the clinical utility of readout-segmented echo-planar imaging (RS-EPI) with single-shot echo-planar imaging (SS-EPI) in diagnosing early prostatic cancers.Materials and Methods: Twenty surgically-proved early prostate cancer patients were collected in this retrospective study. T2WI, RS-EPI and SS-EPI were evaluated by two blinded radiologists. By using 6 sub-region classification method the possibility of the presence of cancer at each sub-region was scored according to the PI-RADS system. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic efficacy of the following 6 protocols: T2WI alone (protocol 1), SS-EPI alone (protocol 2), RS-EPI (protocol 3), a combination of T2WI and SS-EPI (protocol 4) and a combination of T2WI and RS-EPI (protocol 5).Results: The area under the ROC curve (Az) of protocol 1 to protocol 5 for region-based analysis were 0.789, 0.790, 0.874, 0.838, 0.881, respectively. ROC analysis revealed significant differences between protocol 1 and 3, 4, 5, and between protocol 2 and 3, 4, and between protocol 4 and 5 (P<0.05). While the difference between protocol 1 and 2, between 3 and 4, 5 has no statistical significance (P>0.05).Conclusions: The combination of T2WI and DWI can improve the diagnosis ability of early prostate cancers. Combination of T2WI and RS-EPI is a more effective approach than combination of T2WI and SS-EPI for the detection of early prostate cancers.
[Keywords] Prostatic neoplasms；Magnetic resonance imaging；Diffusion weighted imaging

MIN Xiang-de Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

WANG Liang* Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

FENG Zhao-yan Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

LI Liang Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

CAI Jie Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

DENG Ming Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

LI Ba-sen Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

KE Zan Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

FENG Ding-yi Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

*Correspondence to: Wang L, E-mail: wang6@tjh.tjmu.edu.cn

Conflicts of interest   None.

Received  2014-11-05
Accepted  2014-12-30
DOI: 10.3969/j.issn.1674-8034.2015.04.010
DOI:10.3969/j.issn.1674-8034.2015.04.010.

[1]
Doo KW, Sung DJ, Park BJ, et al. Detectability of low and intermediate or high risk prostate cancer with combined T2-weighted and diffusion-weighted MRI. European radiology, 2012, 22(8): 1812-1819.
[2]
Wu LM, Xu JR, Ye YQ, et al. The clinical value of diffusion-weighted imaging in combination with T2-weighted imaging in diagnosing prostate carcinoma: a systematic review and meta-analysis. AJR Am J Roentgenol, 2012, 199(1): 103-110.
[3]
闵祥德，王良，冯朝燕，等. RS-EPI序列在前列腺肿瘤DWI中的临床应用价值．放射学实践, 2014(5): 491-495.
[4]
冯朝燕，王良,闵祥德，等．分段读出扩散加权成像序列表观扩散系数在前列腺癌鉴别诊断中的价值．中华放射学杂志, 2014, 48(10): 841-843.
[5]
Barentsz JO, Richenberg J, Clements R, et al. ESUR prostate MR guidelines 2012. European radiology, 2012, 22(4): 746-757.
[6]
Roethke MC, Kuru TH, Schultze S, et al. Evaluation of the ESUR PI-RADS scoring system for multiparametric MRI of the prostate with targeted MR/TRUS fusion-guided biopsy at 3.0 Tesla. European radiology, 2014, 24(2): 344-352.
[7]
Schimmoller L, Quentin M, Arsov C, et al. MR-sequences for prostate cancer diagnostics: validation based on the PI-RADS scoring system and targeted MR-guided in-bore biopsy. European radiology, 2014, 24(10): 2582-2589.
[8]
王利伟，王牧，王绍娟，等. MR扩散加权成像诊断前列腺癌的价值分析．磁共振成像, 2014, 5(3): 198-201.
[9]
王翠艳，朱向玉，王静，等．表观扩散系数鉴别前列腺中央腺体癌和前列腺增生的价值．磁共振成像, 2010, 1(4): 268-271.
[10]
沈钧康，赵文露，杨毅，等. 1.5T MR功能成像序列联合T2WI对前列腺癌筛查的临床价值．中华放射学杂志, 2014, 48(1): 38-42.
[11]
中华放射学杂志前列腺疾病诊疗工作组，中华放射学杂志编辑委员会．前列腺癌MR检查和诊断共识．中华放射学杂志, 2014, 48(7): 531-534.
[12]
梁宇霆，靳二虎，张艺，等．磁共振扩散加权成像在前列腺癌检出和鉴别诊断中的价值．磁共振成像, 2010, 1(4): 272-276.
[13]
Baur AD, Maxeiner A, Franiel T, et al. Evaluation of the prostate imaging reporting and data system for the detection of prostate cancer by the results of targeted biopsy of the prostate. Investigative radiology, 2014, 49(6): 411-420.
[14]
周婷婷，王建良，沈纪芳，等. MR扩散加权成像在早期前列腺癌诊断中的价值．临床放射学杂志, 2014(7): 1035-1039.
[15]
Porter DA, Heidemann RM.High resolution diffusion-weighted imaging using readout-segmented echo-planar imaging, parallel imaging and a two-dimensional navigator-based reacquisition. Magnetic resonance in medicine: official journal of the Society of Magnetic Resonance in Medicine/Society of Magnetic Resonance in Medicine, 2009, 62(2): 468-475.

PREV The correlation between DCE-MRI parameters and pathological characteristics in rectal cancer
NEXT Research of magnetic resonance perfusion weighted imaging in the characteristics of cervical cancer
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn