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• Clinical Article •
Evaluation of T2WI and readout-segmented echo-planar imaging in diagnosing early prostate cancers: a study based on PI-RADS system
MIN Xiang-de  WANG Liang  FENG Zhao-yan  LI Liang  CAI Jie  DENG Ming  LI Ba-sen  KE Zan  FENG Ding-yi 

DOI:10.3969/j.issn.1674-8034.2015.04.010.


[Abstract] Objectives: To compare the clinical utility of readout-segmented echo-planar imaging (RS-EPI) with single-shot echo-planar imaging (SS-EPI) in diagnosing early prostatic cancers.Materials and Methods: Twenty surgically-proved early prostate cancer patients were collected in this retrospective study. T2WI, RS-EPI and SS-EPI were evaluated by two blinded radiologists. By using 6 sub-region classification method the possibility of the presence of cancer at each sub-region was scored according to the PI-RADS system. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic efficacy of the following 6 protocols: T2WI alone (protocol 1), SS-EPI alone (protocol 2), RS-EPI (protocol 3), a combination of T2WI and SS-EPI (protocol 4) and a combination of T2WI and RS-EPI (protocol 5).Results: The area under the ROC curve (Az) of protocol 1 to protocol 5 for region-based analysis were 0.789, 0.790, 0.874, 0.838, 0.881, respectively. ROC analysis revealed significant differences between protocol 1 and 3, 4, 5, and between protocol 2 and 3, 4, and between protocol 4 and 5 (P<0.05). While the difference between protocol 1 and 2, between 3 and 4, 5 has no statistical significance (P>0.05).Conclusions: The combination of T2WI and DWI can improve the diagnosis ability of early prostate cancers. Combination of T2WI and RS-EPI is a more effective approach than combination of T2WI and SS-EPI for the detection of early prostate cancers.
[Keywords] Prostatic neoplasms；Magnetic resonance imaging；Diffusion weighted imaging

MIN Xiang-de Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

WANG Liang* Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

FENG Zhao-yan Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

LI Liang Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

CAI Jie Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

DENG Ming Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

LI Ba-sen Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

KE Zan Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

FENG Ding-yi Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

*Correspondence to: Wang L, E-mail: wang6@tjh.tjmu.edu.cn

Conflicts of interest   None.

Received  2014-11-05
Accepted  2014-12-30
DOI: 10.3969/j.issn.1674-8034.2015.04.010
DOI:10.3969/j.issn.1674-8034.2015.04.010.

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